Cytochrome P450 Complement May Contribute to Niche Adaptation in <i>Serpula</i> Wood-Decay Fungi
<i>Serpula</i> wood-decay fungi occupy a diverse range of natural and man-made ecological niches. <i>Serpula himantioides</i> is a forest-floor generalist with global coverage and strong antagonistic ability, while closely related species <i>Serpula lacrymans</i>...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Journal of Fungi |
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| Online Access: | https://www.mdpi.com/2309-608X/8/3/283 |
| _version_ | 1797446485791473664 |
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| author | Andrew Cowan Inger Skrede Suzy Clare Moody |
| author_facet | Andrew Cowan Inger Skrede Suzy Clare Moody |
| author_sort | Andrew Cowan |
| collection | DOAJ |
| description | <i>Serpula</i> wood-decay fungi occupy a diverse range of natural and man-made ecological niches. <i>Serpula himantioides</i> is a forest-floor generalist with global coverage and strong antagonistic ability, while closely related species <i>Serpula lacrymans</i> contains specialist sister strains with widely differing ecologies. <i>Serpula lacrymans</i> var. <i>shastensis</i> is a forest-floor specialist in terms of resource preference and geographic coverage, while <i>Serpula lacrymans</i> var. <i>lacrymans</i> has successfully invaded the built environment and occupies a building-timber niche. To increase understanding of the cellular machinery required for niche adaptation, a detailed study of the P450 complement of these three strains was undertaken. Cytochrome P450 monooxygenases are present in all fungi and typically seen in high numbers in wood decay species, with putative roles in breakdown of plant extractives and lignocellulose metabolism. Investigating the genomes of these related yet ecologically diverse fungi revealed a high level of concordance in P450 complement, but with key differences in P450 family representation and expression during growth on wood, suggesting P450 proteins may play a role in niche adaptation. Gene expansion of certain key P450 families was noted, further supporting an important role for these proteins during wood decay. The generalist species <i>S. himantioides</i> was found to have the most P450 genes with the greatest family diversity and the highest number of P450 protein families expressed during wood decay. |
| first_indexed | 2024-03-09T13:42:02Z |
| format | Article |
| id | doaj.art-2310af52016e44668b18a140695bee9c |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-09T13:42:02Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-2310af52016e44668b18a140695bee9c2023-11-30T21:05:16ZengMDPI AGJournal of Fungi2309-608X2022-03-018328310.3390/jof8030283Cytochrome P450 Complement May Contribute to Niche Adaptation in <i>Serpula</i> Wood-Decay FungiAndrew Cowan0Inger Skrede1Suzy Clare Moody2Faculty of Sport, Health and Social Science, Solent University, Southampton SO14 0YN, UKDepartment of Biosciences, University of Oslo, NO-0316 Oslo, NorwayFaculty of Science, Engineering and Computing, Kingston University, Kingston-Upon-Thames KT1 2EE, UK<i>Serpula</i> wood-decay fungi occupy a diverse range of natural and man-made ecological niches. <i>Serpula himantioides</i> is a forest-floor generalist with global coverage and strong antagonistic ability, while closely related species <i>Serpula lacrymans</i> contains specialist sister strains with widely differing ecologies. <i>Serpula lacrymans</i> var. <i>shastensis</i> is a forest-floor specialist in terms of resource preference and geographic coverage, while <i>Serpula lacrymans</i> var. <i>lacrymans</i> has successfully invaded the built environment and occupies a building-timber niche. To increase understanding of the cellular machinery required for niche adaptation, a detailed study of the P450 complement of these three strains was undertaken. Cytochrome P450 monooxygenases are present in all fungi and typically seen in high numbers in wood decay species, with putative roles in breakdown of plant extractives and lignocellulose metabolism. Investigating the genomes of these related yet ecologically diverse fungi revealed a high level of concordance in P450 complement, but with key differences in P450 family representation and expression during growth on wood, suggesting P450 proteins may play a role in niche adaptation. Gene expansion of certain key P450 families was noted, further supporting an important role for these proteins during wood decay. The generalist species <i>S. himantioides</i> was found to have the most P450 genes with the greatest family diversity and the highest number of P450 protein families expressed during wood decay.https://www.mdpi.com/2309-608X/8/3/283P450dry rotadaptation<i>Serpula himantioides</i><i>Serpula lacrymans</i> var. <i>shastensis</i><i>Serpula lacrymans</i> var. <i>lacrymans</i> |
| spellingShingle | Andrew Cowan Inger Skrede Suzy Clare Moody Cytochrome P450 Complement May Contribute to Niche Adaptation in <i>Serpula</i> Wood-Decay Fungi Journal of Fungi P450 dry rot adaptation <i>Serpula himantioides</i> <i>Serpula lacrymans</i> var. <i>shastensis</i> <i>Serpula lacrymans</i> var. <i>lacrymans</i> |
| title | Cytochrome P450 Complement May Contribute to Niche Adaptation in <i>Serpula</i> Wood-Decay Fungi |
| title_full | Cytochrome P450 Complement May Contribute to Niche Adaptation in <i>Serpula</i> Wood-Decay Fungi |
| title_fullStr | Cytochrome P450 Complement May Contribute to Niche Adaptation in <i>Serpula</i> Wood-Decay Fungi |
| title_full_unstemmed | Cytochrome P450 Complement May Contribute to Niche Adaptation in <i>Serpula</i> Wood-Decay Fungi |
| title_short | Cytochrome P450 Complement May Contribute to Niche Adaptation in <i>Serpula</i> Wood-Decay Fungi |
| title_sort | cytochrome p450 complement may contribute to niche adaptation in i serpula i wood decay fungi |
| topic | P450 dry rot adaptation <i>Serpula himantioides</i> <i>Serpula lacrymans</i> var. <i>shastensis</i> <i>Serpula lacrymans</i> var. <i>lacrymans</i> |
| url | https://www.mdpi.com/2309-608X/8/3/283 |
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