LncRNA SNHG9 is downregulated in osteoarthritis and inhibits chondrocyte apoptosis by downregulating miR-34a through methylation
Abstract Background Our preliminary RNA-Seq data revealed altered expression of small nucleolar RNA host gene 9 (SNHG9) in osteoarthritis (OA) and its reverse correlation with miR-34a, which can regulate chondrocyte apoptosis in rat OA model. This study was therefore carried out to investigate the p...
Main Authors: | Hongfei Zhang, Jinglian Li, Weiguang Shao, Naipeng Shen |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-08-01
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Series: | BMC Musculoskeletal Disorders |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12891-020-03497-7 |
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