A transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication

A transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication

Abstract Background Tunneling nanotubes (TNTs) are naturally-occurring filamentous actin-based membranous extensions that form across a wide spectrum of mammalian cell types to facilitate long-range intercellular communication. Valid assays are needed to accurately assess the downstream effects of T...

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Bibliographic Details
Main Authors: Venugopal Thayanithy, Patrick O’Hare, Phillip Wong, Xianda Zhao, Clifford J. Steer, Subbaya Subramanian, Emil Lou
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Cell Communication and Signaling
Subjects:
Tunneling nanotubes
Membrane nanotubes
Intercellular transfer
Intercellular communication
Transwell assay
Exosomes
Online Access:http://link.springer.com/article/10.1186/s12964-017-0201-2

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