Prevalence of HLA-B*57:01 allele in HIV-positive and HIV-negative population of eastern India: An epidemiological study

Prevalence of HLA-B*57:01 allele in HIV-positive and HIV-negative population of eastern India: An epidemiological study

Introduction: The nucleoside analogue reverse-transcriptase inhibitor Abacavir has potent antiviral activity against HIV; however, 5–8% patients develop hypersensitivity reactions within six weeks of treatment. The presence of the HLA-B*57:01 allele is strongly associated with the risk of Abacavir-a...

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Bibliographic Details
Main Authors: Abhilasha Gautam, Jaya Chakravarty, Ankita Chourasia, Saurabh Sharma, Tanmoy Sarkar, Parimal Das
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Clinical Epidemiology and Global Health
Subjects:
Abacavir
HIV
HLA-B*57:01 allele
Hypersensitivity reaction
India
Online Access:http://www.sciencedirect.com/science/article/pii/S221339842200224X

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