Primary thyroid lymphoma: A rare disease
Primary thyroid lymphomas are rare neoplasms comprising of 1-5% of thyroid malignancies. These are predominantly B-cell in origin. Here, we report a case of 60 years lady, a known case of lymphocytic thyroiditis, diagnosed as thyroid lymphoma (diffuse large B-cell) on fine needle aspiration and conf...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Journal of Cytology |
| Subjects: | |
| Online Access: | http://www.jcytol.org/article.asp?issn=0970-9371;year=2014;volume=31;issue=4;spage=218;epage=220;aulast=Verma |
| _version_ | 1818056473348931584 |
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| author | Deepti Verma Vandana Puri Shilpi Agarwal Aasha Bhaskar |
| author_facet | Deepti Verma Vandana Puri Shilpi Agarwal Aasha Bhaskar |
| author_sort | Deepti Verma |
| collection | DOAJ |
| description | Primary thyroid lymphomas are rare neoplasms comprising of 1-5% of thyroid malignancies. These are predominantly B-cell in origin. Here, we report a case of 60 years lady, a known case of lymphocytic thyroiditis, diagnosed as thyroid lymphoma (diffuse large B-cell) on fine needle aspiration and confirmed histopathogically and immunohistochemically. She presented with a sudden increase in thyroid swelling. Fine needle aspiration performed showed highly cellular smears comprising predominantly of the monomorphic population of medium to large sized lymphoid cells with high nuclear/cytoplasmic ratio and scant cytoplasm. A possibility of thyroid lymphoma possibly diffuse large B-cell lymphoma was suggested which was later confirmed on biopsy. Fine needle aspiration provides an easy mode for diagnosing large cell lymphoma like diffuse large B-cell. Hence, an early diagnosis is possible for a timely intervention. Also, cases of lymphocytic thyroiditis should be regularly followed for the development of lymphoma. |
| first_indexed | 2024-12-10T12:29:24Z |
| format | Article |
| id | doaj.art-23177e8390a647e7889f990e98e638e2 |
| institution | Directory Open Access Journal |
| issn | 0970-9371 |
| language | English |
| last_indexed | 2024-12-10T12:29:24Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cytology |
| spelling | doaj.art-23177e8390a647e7889f990e98e638e22022-12-22T01:48:52ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93712014-01-0131421822010.4103/0970-9371.151139Primary thyroid lymphoma: A rare diseaseDeepti VermaVandana PuriShilpi AgarwalAasha BhaskarPrimary thyroid lymphomas are rare neoplasms comprising of 1-5% of thyroid malignancies. These are predominantly B-cell in origin. Here, we report a case of 60 years lady, a known case of lymphocytic thyroiditis, diagnosed as thyroid lymphoma (diffuse large B-cell) on fine needle aspiration and confirmed histopathogically and immunohistochemically. She presented with a sudden increase in thyroid swelling. Fine needle aspiration performed showed highly cellular smears comprising predominantly of the monomorphic population of medium to large sized lymphoid cells with high nuclear/cytoplasmic ratio and scant cytoplasm. A possibility of thyroid lymphoma possibly diffuse large B-cell lymphoma was suggested which was later confirmed on biopsy. Fine needle aspiration provides an easy mode for diagnosing large cell lymphoma like diffuse large B-cell. Hence, an early diagnosis is possible for a timely intervention. Also, cases of lymphocytic thyroiditis should be regularly followed for the development of lymphoma.http://www.jcytol.org/article.asp?issn=0970-9371;year=2014;volume=31;issue=4;spage=218;epage=220;aulast=VermaLymphoma; primary; thyroid; thyroiditis; fine needle aspiration cytology |
| spellingShingle | Deepti Verma Vandana Puri Shilpi Agarwal Aasha Bhaskar Primary thyroid lymphoma: A rare disease Journal of Cytology Lymphoma; primary; thyroid; thyroiditis; fine needle aspiration cytology |
| title | Primary thyroid lymphoma: A rare disease |
| title_full | Primary thyroid lymphoma: A rare disease |
| title_fullStr | Primary thyroid lymphoma: A rare disease |
| title_full_unstemmed | Primary thyroid lymphoma: A rare disease |
| title_short | Primary thyroid lymphoma: A rare disease |
| title_sort | primary thyroid lymphoma a rare disease |
| topic | Lymphoma; primary; thyroid; thyroiditis; fine needle aspiration cytology |
| url | http://www.jcytol.org/article.asp?issn=0970-9371;year=2014;volume=31;issue=4;spage=218;epage=220;aulast=Verma |
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