Emergence of High-Level Cefiderocol Resistance in Carbapenem-Resistant Klebsiella pneumoniae from Bloodstream Infections in Patients with Hematologic Malignancies in China

Emergence of High-Level Cefiderocol Resistance in Carbapenem-Resistant Klebsiella pneumoniae from Bloodstream Infections in Patients with Hematologic Malignancies in China

ABSTRACT Cefiderocol is a novel siderophore cephalosporin exhibiting potent antimicrobial activities. Although cefiderocol has not been approved in China, resistance is emerging. A multicenter study was performed to evaluate the cefiderocol resistance in carbapenem-resistant Klebsiella pneumoniae (C...

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Bibliographic Details
Main Authors: Peng Lan, Ye Lu, Zhongju Chen, Xueqing Wu, Xiaoting Hua, Yan Jiang, Jiancang Zhou, Yunsong Yu
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
bloodstream infections
cefiderocol
CRKP
NDM
CirA
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00084-22

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