A Development Of Electrode Probes For Imaging Precancerous Lesions With Electrical Impedance Tomography Technique: A Phantom Study
Cervical abnormality screening can reduce the risk of getting cancer. Screening methods mostly depend on laboratory investigation which requires equipment, time, and pathologist experience. Electrical bioimpedance has been reported that can be used to identify the presence of cervical intraepitheli...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tamkang University Press
2023-08-01
|
| Series: | Journal of Applied Science and Engineering |
| Subjects: | |
| Online Access: | http://jase.tku.edu.tw/articles/jase-202401-27-1-0006 |
| _version_ | 1797740364684066816 |
|---|---|
| author | Napatsawan Ngamdi Jaruwan Sriwilai Therdkiat Trongwongsa Taweechai Ouypornkochagorn |
| author_facet | Napatsawan Ngamdi Jaruwan Sriwilai Therdkiat Trongwongsa Taweechai Ouypornkochagorn |
| author_sort | Napatsawan Ngamdi |
| collection | DOAJ |
| description | Cervical abnormality screening can reduce the risk of getting cancer. Screening methods mostly depend on
laboratory investigation which requires equipment, time, and pathologist experience. Electrical bioimpedance has been reported that can be used to identify the presence of cervical intraepithelial neoplasia (CIN) since the conductivity of CIN could be 4-5 times higher than that of normal tissue. In this study, an electrode probe having 8 round electrodes is developed with 1.5 mm-electrode distance. Tissue conductivity can be directly estimated with the probe based on the four-point measurement method, and the image of conductivity distribution can be reconstructed at the same time. The simulation result showed that when tissue thickness was thicker than 4 mm, the commonly-used formula for estimating conductivity is applicable regardless of the electrode shape, but a correction factor was needed with a value up to 1.2 when the thickness was down to 1 mm. The localization performance of the reconstruction images was investigated in a phantom experiment – on a piece of sausage with a burning spot on the surface. Five current excitations were performed from 2 kHz to 125 kHz. The burning surface could be located with a localization error of 0.23 mm with a frequency higher than 2 kHz. However, artifacts were still observable in the images at the boundary region of the electrode array. Thus, increasing the number of electrodes and increasing the probe tip area or decreasing the electrode diameter are still recommended. |
| first_indexed | 2024-03-12T14:11:23Z |
| format | Article |
| id | doaj.art-23192348b698489997322c5465a8dde7 |
| institution | Directory Open Access Journal |
| issn | 2708-9967 2708-9975 |
| language | English |
| last_indexed | 2024-03-12T14:11:23Z |
| publishDate | 2023-08-01 |
| publisher | Tamkang University Press |
| record_format | Article |
| series | Journal of Applied Science and Engineering |
| spelling | doaj.art-23192348b698489997322c5465a8dde72023-08-21T08:24:00ZengTamkang University PressJournal of Applied Science and Engineering2708-99672708-99752023-08-012711901191010.6180/jase.202401_27(1).0006A Development Of Electrode Probes For Imaging Precancerous Lesions With Electrical Impedance Tomography Technique: A Phantom StudyNapatsawan Ngamdi0Jaruwan Sriwilai1Therdkiat Trongwongsa2Taweechai Ouypornkochagorn3Department of Biomedical Engineering, Faculty of Engineering, Srinakharinwirot University, ThailandDepartment of Pathology, Faculty of Medicine, Srinakharinwirot University, ThailandDepartment of Pathology, Faculty of Medicine, Srinakharinwirot University, ThailandDepartment of Biomedical Engineering, Faculty of Engineering, Srinakharinwirot University, ThailandCervical abnormality screening can reduce the risk of getting cancer. Screening methods mostly depend on laboratory investigation which requires equipment, time, and pathologist experience. Electrical bioimpedance has been reported that can be used to identify the presence of cervical intraepithelial neoplasia (CIN) since the conductivity of CIN could be 4-5 times higher than that of normal tissue. In this study, an electrode probe having 8 round electrodes is developed with 1.5 mm-electrode distance. Tissue conductivity can be directly estimated with the probe based on the four-point measurement method, and the image of conductivity distribution can be reconstructed at the same time. The simulation result showed that when tissue thickness was thicker than 4 mm, the commonly-used formula for estimating conductivity is applicable regardless of the electrode shape, but a correction factor was needed with a value up to 1.2 when the thickness was down to 1 mm. The localization performance of the reconstruction images was investigated in a phantom experiment – on a piece of sausage with a burning spot on the surface. Five current excitations were performed from 2 kHz to 125 kHz. The burning surface could be located with a localization error of 0.23 mm with a frequency higher than 2 kHz. However, artifacts were still observable in the images at the boundary region of the electrode array. Thus, increasing the number of electrodes and increasing the probe tip area or decreasing the electrode diameter are still recommended.http://jase.tku.edu.tw/articles/jase-202401-27-1-0006electrode probecervical precancerous tissuesreconstructiontissue conductivity |
| spellingShingle | Napatsawan Ngamdi Jaruwan Sriwilai Therdkiat Trongwongsa Taweechai Ouypornkochagorn A Development Of Electrode Probes For Imaging Precancerous Lesions With Electrical Impedance Tomography Technique: A Phantom Study Journal of Applied Science and Engineering electrode probe cervical precancerous tissues reconstruction tissue conductivity |
| title | A Development Of Electrode Probes For Imaging Precancerous Lesions With Electrical Impedance Tomography Technique: A Phantom Study |
| title_full | A Development Of Electrode Probes For Imaging Precancerous Lesions With Electrical Impedance Tomography Technique: A Phantom Study |
| title_fullStr | A Development Of Electrode Probes For Imaging Precancerous Lesions With Electrical Impedance Tomography Technique: A Phantom Study |
| title_full_unstemmed | A Development Of Electrode Probes For Imaging Precancerous Lesions With Electrical Impedance Tomography Technique: A Phantom Study |
| title_short | A Development Of Electrode Probes For Imaging Precancerous Lesions With Electrical Impedance Tomography Technique: A Phantom Study |
| title_sort | development of electrode probes for imaging precancerous lesions with electrical impedance tomography technique a phantom study |
| topic | electrode probe cervical precancerous tissues reconstruction tissue conductivity |
| url | http://jase.tku.edu.tw/articles/jase-202401-27-1-0006 |
| work_keys_str_mv | AT napatsawanngamdi adevelopmentofelectrodeprobesforimagingprecancerouslesionswithelectricalimpedancetomographytechniqueaphantomstudy AT jaruwansriwilai adevelopmentofelectrodeprobesforimagingprecancerouslesionswithelectricalimpedancetomographytechniqueaphantomstudy AT therdkiattrongwongsa adevelopmentofelectrodeprobesforimagingprecancerouslesionswithelectricalimpedancetomographytechniqueaphantomstudy AT taweechaiouypornkochagorn adevelopmentofelectrodeprobesforimagingprecancerouslesionswithelectricalimpedancetomographytechniqueaphantomstudy AT napatsawanngamdi developmentofelectrodeprobesforimagingprecancerouslesionswithelectricalimpedancetomographytechniqueaphantomstudy AT jaruwansriwilai developmentofelectrodeprobesforimagingprecancerouslesionswithelectricalimpedancetomographytechniqueaphantomstudy AT therdkiattrongwongsa developmentofelectrodeprobesforimagingprecancerouslesionswithelectricalimpedancetomographytechniqueaphantomstudy AT taweechaiouypornkochagorn developmentofelectrodeprobesforimagingprecancerouslesionswithelectricalimpedancetomographytechniqueaphantomstudy |