Analysis of the effectiveness and long-term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary disease
Aim. To assess the long-term clinical results of vaccination with pneumococcal polysaccharide and conjugated polysaccharide vaccines in the separate and sequential use, by determining the optimal vaccination schedule in adult patients with chronic obstructive pulmonary disease (COPD) and to investig...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2017-12-01
|
| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/32344 |
| _version_ | 1819026193650810880 |
|---|---|
| author | A D Protasov A V Zhestkov M P Kostinov M L Shteiner Yu V Tezikov I S Lipatov N E Yastrebova A M Kostinova A A Ryzhov V B Polishchuk |
| author_facet | A D Protasov A V Zhestkov M P Kostinov M L Shteiner Yu V Tezikov I S Lipatov N E Yastrebova A M Kostinova A A Ryzhov V B Polishchuk |
| author_sort | A D Protasov |
| collection | DOAJ |
| description | Aim. To assess the long-term clinical results of vaccination with pneumococcal polysaccharide and conjugated polysaccharide vaccines in the separate and sequential use, by determining the optimal vaccination schedule in adult patients with chronic obstructive pulmonary disease (COPD) and to investigate adaptive immunity levels. Subjects and methods. The clinical effects of vaccination were evaluated in patients with COPD within 1 and 4 years after immunization against pneumococcal infection using various schemes, as well as the time course of changes in adaptive immunity indicators was examined. Results. Four years after vaccination, the 13-valent pneumococcal conjugate vaccine (PCV13)/23-valent pneumococcal polysaccharide vaccine (PPV23) group showed a decline in the number of patients with COPD exacerbations by 50% (p |
| first_indexed | 2024-12-21T05:22:41Z |
| format | Article |
| id | doaj.art-232158e71c954c4d9d2e26687e8e7d51 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-21T05:22:41Z |
| publishDate | 2017-12-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-232158e71c954c4d9d2e26687e8e7d512022-12-21T19:14:47Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422017-12-018912-216517410.17116/terarkh20178912165-17429344Analysis of the effectiveness and long-term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary diseaseA D ProtasovA V ZhestkovM P KostinovM L ShteinerYu V TezikovI S LipatovN E YastrebovaA M KostinovaA A RyzhovV B PolishchukAim. To assess the long-term clinical results of vaccination with pneumococcal polysaccharide and conjugated polysaccharide vaccines in the separate and sequential use, by determining the optimal vaccination schedule in adult patients with chronic obstructive pulmonary disease (COPD) and to investigate adaptive immunity levels. Subjects and methods. The clinical effects of vaccination were evaluated in patients with COPD within 1 and 4 years after immunization against pneumococcal infection using various schemes, as well as the time course of changes in adaptive immunity indicators was examined. Results. Four years after vaccination, the 13-valent pneumococcal conjugate vaccine (PCV13)/23-valent pneumococcal polysaccharide vaccine (PPV23) group showed a decline in the number of patients with COPD exacerbations by 50% (phttps://ter-arkhiv.ru/0040-3660/article/view/32344chronic obstructive pulmonary diseasevaccinationpneumococcal polysaccharide vaccineconjugated pneumococcal polysaccharide vaccineclinical efficacylong-term resultsadaptive immunity |
| spellingShingle | A D Protasov A V Zhestkov M P Kostinov M L Shteiner Yu V Tezikov I S Lipatov N E Yastrebova A M Kostinova A A Ryzhov V B Polishchuk Analysis of the effectiveness and long-term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary disease Терапевтический архив chronic obstructive pulmonary disease vaccination pneumococcal polysaccharide vaccine conjugated pneumococcal polysaccharide vaccine clinical efficacy long-term results adaptive immunity |
| title | Analysis of the effectiveness and long-term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary disease |
| title_full | Analysis of the effectiveness and long-term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary disease |
| title_fullStr | Analysis of the effectiveness and long-term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary disease |
| title_full_unstemmed | Analysis of the effectiveness and long-term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary disease |
| title_short | Analysis of the effectiveness and long-term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary disease |
| title_sort | analysis of the effectiveness and long term results of formation of adaptive immunity in the use of various medications and vaccination schemes against pneumococcal infection in patients with chronic obstructive pulmonary disease |
| topic | chronic obstructive pulmonary disease vaccination pneumococcal polysaccharide vaccine conjugated pneumococcal polysaccharide vaccine clinical efficacy long-term results adaptive immunity |
| url | https://ter-arkhiv.ru/0040-3660/article/view/32344 |
| work_keys_str_mv | AT adprotasov analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT avzhestkov analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT mpkostinov analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT mlshteiner analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT yuvtezikov analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT islipatov analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT neyastrebova analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT amkostinova analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT aaryzhov analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease AT vbpolishchuk analysisoftheeffectivenessandlongtermresultsofformationofadaptiveimmunityintheuseofvariousmedicationsandvaccinationschemesagainstpneumococcalinfectioninpatientswithchronicobstructivepulmonarydisease |