Aripiprazole in the acute and maintenance phase of bipolar I disorder
Melanie Zupancic1, Misty L Gonzalez2,31Southern Illinois University School of Medicine, 2Division of Medicine Psychiatry, Southern Illinois University School of Medicine, 3Southern Illinois University Edwardsville School of Pharmacy, Southern Illinois University Edwardsville, Springfield, IL, USAAbs...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2012-01-01
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| Series: | Therapeutics and Clinical Risk Management |
| Online Access: | http://www.dovepress.com/aripiprazole-in-the-acute-and-maintenance-phase-of-bipolar-i-disorder-a9045 |
| _version_ | 1818580554411409408 |
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| author | Zupancic M Gonzalez ML |
| author_facet | Zupancic M Gonzalez ML |
| author_sort | Zupancic M |
| collection | DOAJ |
| description | Melanie Zupancic1, Misty L Gonzalez2,31Southern Illinois University School of Medicine, 2Division of Medicine Psychiatry, Southern Illinois University School of Medicine, 3Southern Illinois University Edwardsville School of Pharmacy, Southern Illinois University Edwardsville, Springfield, IL, USAAbstract: Bipolar affective disorder is a disabling illness with substantial morbidity and many management challenges. Traditional mood stabilizers such as lithium, valproate, and carbamazepine are often inadequate in controlling symptoms both during the acute and maintenance phase of treatment. Aripiprazole is a second-generation antipsychotic with a unique mechanism of action. Evidence suggests that it is effective in acute manic and mixed states. There are limited data to suggest its efficacy as a maintenance agent. Future studies will be needed to better define the role of aripiprazole relative to other traditional pharmacologic agents.Keywords: aripiprazole, bipolar disorder, acute treatment, maintenance treatment |
| first_indexed | 2024-12-16T07:19:27Z |
| format | Article |
| id | doaj.art-2325f7bd5c1a48c69d3d0d74591f5ea7 |
| institution | Directory Open Access Journal |
| issn | 1176-6336 1178-203X |
| language | English |
| last_indexed | 2024-12-16T07:19:27Z |
| publishDate | 2012-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Therapeutics and Clinical Risk Management |
| spelling | doaj.art-2325f7bd5c1a48c69d3d0d74591f5ea72022-12-21T22:39:41ZengDove Medical PressTherapeutics and Clinical Risk Management1176-63361178-203X2012-01-012012default16Aripiprazole in the acute and maintenance phase of bipolar I disorderZupancic MGonzalez MLMelanie Zupancic1, Misty L Gonzalez2,31Southern Illinois University School of Medicine, 2Division of Medicine Psychiatry, Southern Illinois University School of Medicine, 3Southern Illinois University Edwardsville School of Pharmacy, Southern Illinois University Edwardsville, Springfield, IL, USAAbstract: Bipolar affective disorder is a disabling illness with substantial morbidity and many management challenges. Traditional mood stabilizers such as lithium, valproate, and carbamazepine are often inadequate in controlling symptoms both during the acute and maintenance phase of treatment. Aripiprazole is a second-generation antipsychotic with a unique mechanism of action. Evidence suggests that it is effective in acute manic and mixed states. There are limited data to suggest its efficacy as a maintenance agent. Future studies will be needed to better define the role of aripiprazole relative to other traditional pharmacologic agents.Keywords: aripiprazole, bipolar disorder, acute treatment, maintenance treatmenthttp://www.dovepress.com/aripiprazole-in-the-acute-and-maintenance-phase-of-bipolar-i-disorder-a9045 |
| spellingShingle | Zupancic M Gonzalez ML Aripiprazole in the acute and maintenance phase of bipolar I disorder Therapeutics and Clinical Risk Management |
| title | Aripiprazole in the acute and maintenance phase of bipolar I disorder |
| title_full | Aripiprazole in the acute and maintenance phase of bipolar I disorder |
| title_fullStr | Aripiprazole in the acute and maintenance phase of bipolar I disorder |
| title_full_unstemmed | Aripiprazole in the acute and maintenance phase of bipolar I disorder |
| title_short | Aripiprazole in the acute and maintenance phase of bipolar I disorder |
| title_sort | aripiprazole in the acute and maintenance phase of bipolar i disorder |
| url | http://www.dovepress.com/aripiprazole-in-the-acute-and-maintenance-phase-of-bipolar-i-disorder-a9045 |
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