Optimizing the use of ketamine to reduce chronic postsurgical pain in women undergoing mastectomy for oncologic indication: study protocol for the KALPAS multicenter randomized controlled trial

Optimizing the use of ketamine to reduce chronic postsurgical pain in women undergoing mastectomy for oncologic indication: study protocol for the KALPAS multicenter randomized controlled trial

Abstract Background Mastectomies are commonly performed and strongly associated with chronic postsurgical pain (CPSP), more specifically termed postmastectomy pain syndrome (PMPS), with 25–60% of patients reporting pain 3 months after surgery. PMPS interferes with function, recovery, and compliance...

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Bibliographic Details
Main Authors: Jing Wang, Lisa V. Doan, Deborah Axelrod, John Rotrosen, Binhuan Wang, Hyung G. Park, Robert R. Edwards, Michele Curatolo, Carina Jackman, Raven Perez, NCATS Trial Innovation Network
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Trials
Subjects:
Postoperative pain
Chronic postsurgical pain
Postmastectomy pain syndrome
Ketamine
Non-opioid
Online Access:https://doi.org/10.1186/s13063-023-07884-y

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