Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological Activates
This work describes the synthesis of novel ligand (H2L2) (4-((2-hydroxy-5-nitrophenyl)imino)methyl)-5(hydroxymethyl)-2methylpyridin-3-ol) type (NOO) donor atoms. When it coordinates with metal ions[V2+, Fe2+,Co2+ and Pt4+] with the general formula K2[M(L2)2].XH2O and K2[VO(L2)(OSO3)].H2O . This li...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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University of Baghdad
2023-04-01
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| Series: | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| Online Access: | https://jih.uobaghdad.edu.iq/index.php/j/article/view/3054 |
| _version_ | 1827962808659083264 |
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| author | Ahmed A. Ismail Sajid M. Lateef |
| author_facet | Ahmed A. Ismail Sajid M. Lateef |
| author_sort | Ahmed A. Ismail |
| collection | DOAJ |
| description |
This work describes the synthesis of novel ligand (H2L2) (4-((2-hydroxy-5-nitrophenyl)imino)methyl)-5(hydroxymethyl)-2methylpyridin-3-ol) type (NOO) donor atoms. When it coordinates with metal ions[V2+, Fe2+,Co2+ and Pt4+] with the general formula K2[M(L2)2].XH2O and K2[VO(L2)(OSO3)].H2O . This ligand can form tridentate structures. The ligand was synthesized from the reaction of pyridoxal hydrochloride with 2-amino-4-nitrophenol in ethanol (as a solvent) at a mole ratio of 1:1 and thoroughly mixed and refluxed for 6-8 hrs . The reaction was monitored using TLC (Ethylactate/hexane 1:1). The structures of the ligand and the complexes were characterised using spectroscopic techniques such as (FT-IR, 1HNMR, 13CNMR, UV-Vis, and Mass spectroscopy). In addition, molar conductance, magnetic susceptibility, elemental analysis, and thermo gravimetric, melting points were also measured for complexes. The antibacterial activities of the obtained products were tested against G- bacteria (Klebsiella pneumoniae and pseudomonas), G+ bacteria (Staphylococcus aureus and Bacillus subtilis). In addition, antifungal action was tested against (Candida albicans). The results were good in both tests.
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| first_indexed | 2024-04-09T16:48:44Z |
| format | Article |
| id | doaj.art-2328a523ff264b3f958720a6f0b0ae1b |
| institution | Directory Open Access Journal |
| issn | 1609-4042 2521-3407 |
| language | English |
| last_indexed | 2024-04-09T16:48:44Z |
| publishDate | 2023-04-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| spelling | doaj.art-2328a523ff264b3f958720a6f0b0ae1b2023-04-22T03:30:04ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072023-04-0136210.30526/36.2.3054Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological ActivatesAhmed A. Ismail0Sajid M. Lateef 1Departmentof Chemistry/ College of Education for pure science Ibn Al-Haitham/ University of Baghdad/ Baghdad/ IraqDepartment of Chemistry, College of Education for Pure Science, University of Diyala, Diyala, Iraq. This work describes the synthesis of novel ligand (H2L2) (4-((2-hydroxy-5-nitrophenyl)imino)methyl)-5(hydroxymethyl)-2methylpyridin-3-ol) type (NOO) donor atoms. When it coordinates with metal ions[V2+, Fe2+,Co2+ and Pt4+] with the general formula K2[M(L2)2].XH2O and K2[VO(L2)(OSO3)].H2O . This ligand can form tridentate structures. The ligand was synthesized from the reaction of pyridoxal hydrochloride with 2-amino-4-nitrophenol in ethanol (as a solvent) at a mole ratio of 1:1 and thoroughly mixed and refluxed for 6-8 hrs . The reaction was monitored using TLC (Ethylactate/hexane 1:1). The structures of the ligand and the complexes were characterised using spectroscopic techniques such as (FT-IR, 1HNMR, 13CNMR, UV-Vis, and Mass spectroscopy). In addition, molar conductance, magnetic susceptibility, elemental analysis, and thermo gravimetric, melting points were also measured for complexes. The antibacterial activities of the obtained products were tested against G- bacteria (Klebsiella pneumoniae and pseudomonas), G+ bacteria (Staphylococcus aureus and Bacillus subtilis). In addition, antifungal action was tested against (Candida albicans). The results were good in both tests. https://jih.uobaghdad.edu.iq/index.php/j/article/view/3054 |
| spellingShingle | Ahmed A. Ismail Sajid M. Lateef Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological Activates Ibn Al-Haitham Journal for Pure and Applied Sciences |
| title | Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological Activates |
| title_full | Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological Activates |
| title_fullStr | Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological Activates |
| title_full_unstemmed | Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological Activates |
| title_short | Synthesis a Novel Complexes of VO(II),Mn(II),Fe(II) ,Co(II), Ni(II), Cu(II)and Pt(IV) Derived from Schiff’s Base of Pyridoxal and 2-amino-4-nitrophenol and Study their Biological Activates |
| title_sort | synthesis a novel complexes of vo ii mn ii fe ii co ii ni ii cu ii and pt iv derived from schiff s base of pyridoxal and 2 amino 4 nitrophenol and study their biological activates |
| url | https://jih.uobaghdad.edu.iq/index.php/j/article/view/3054 |
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