Cryptococcosis as a cause of organizing pneumonia
In cases showing organizing pneumonia (OP) with radiologic findings and pathological images, it is necessary to differentiate between idiopathic and secondary diseases as the cause of OP. Cryptococcus infection as a cause of OP is not well known. We herein report two cases of secondary pulmonary cry...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-01-01
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| Series: | Respiratory Medicine Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007119301029 |
| _version_ | 1818991663307030528 |
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| author | Ayumi Chikumoto Keiji Oishi Kazuki Hamada Kazuki Matsuda Sho Uehara Ryo Suetake Yoshikazu Yamaji Maki Asami-Noyama Nobutaka Edakuni Tsunahiko Hirano Tomoyuki Murakami Kazuto Matsunaga |
| author_facet | Ayumi Chikumoto Keiji Oishi Kazuki Hamada Kazuki Matsuda Sho Uehara Ryo Suetake Yoshikazu Yamaji Maki Asami-Noyama Nobutaka Edakuni Tsunahiko Hirano Tomoyuki Murakami Kazuto Matsunaga |
| author_sort | Ayumi Chikumoto |
| collection | DOAJ |
| description | In cases showing organizing pneumonia (OP) with radiologic findings and pathological images, it is necessary to differentiate between idiopathic and secondary diseases as the cause of OP. Cryptococcus infection as a cause of OP is not well known. We herein report two cases of secondary pulmonary cryptococcosis in immunocompromised patients who showed OP, and the usefulness of bronchoscopy and serum cryptococcal antigen test for an early diagnosis. Common to both cases was that antibiotic therapy and corticosteroid therapy were ineffective, while antifungal agents were effective. In cases of immunocompromised patients who present OP with radiologic findings or pathological images, prompt administration of antifungal treatment at an early stage is important when pulmonary cryptococcosis is identified by bronchoscopy and serum cryptococcal antigen test. Keywords: Cryptococcosis, Organizing pneumonia, Immunocompromised host, Bronchoscopy, Serum cryptococcal antigen test |
| first_indexed | 2024-12-20T20:13:51Z |
| format | Article |
| id | doaj.art-232af39f8a8e4fc3ad871d2e759330e7 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-20T20:13:51Z |
| publishDate | 2019-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-232af39f8a8e4fc3ad871d2e759330e72022-12-21T19:27:46ZengElsevierRespiratory Medicine Case Reports2213-00712019-01-0127Cryptococcosis as a cause of organizing pneumoniaAyumi Chikumoto0Keiji Oishi1Kazuki Hamada2Kazuki Matsuda3Sho Uehara4Ryo Suetake5Yoshikazu Yamaji6Maki Asami-Noyama7Nobutaka Edakuni8Tsunahiko Hirano9Tomoyuki Murakami10Kazuto Matsunaga11Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Medicine and Clinical Science, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan; Corresponding author. Tel.: +81 836 22 2248; fax: +81 836 22 2246.Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanDepartment of Pathology, National Hospital Organization Kanmon Medical Center, 1-1 Chofusotouracho, Shimonoseki, Yamaguchi 752-8510, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, JapanIn cases showing organizing pneumonia (OP) with radiologic findings and pathological images, it is necessary to differentiate between idiopathic and secondary diseases as the cause of OP. Cryptococcus infection as a cause of OP is not well known. We herein report two cases of secondary pulmonary cryptococcosis in immunocompromised patients who showed OP, and the usefulness of bronchoscopy and serum cryptococcal antigen test for an early diagnosis. Common to both cases was that antibiotic therapy and corticosteroid therapy were ineffective, while antifungal agents were effective. In cases of immunocompromised patients who present OP with radiologic findings or pathological images, prompt administration of antifungal treatment at an early stage is important when pulmonary cryptococcosis is identified by bronchoscopy and serum cryptococcal antigen test. Keywords: Cryptococcosis, Organizing pneumonia, Immunocompromised host, Bronchoscopy, Serum cryptococcal antigen testhttp://www.sciencedirect.com/science/article/pii/S2213007119301029 |
| spellingShingle | Ayumi Chikumoto Keiji Oishi Kazuki Hamada Kazuki Matsuda Sho Uehara Ryo Suetake Yoshikazu Yamaji Maki Asami-Noyama Nobutaka Edakuni Tsunahiko Hirano Tomoyuki Murakami Kazuto Matsunaga Cryptococcosis as a cause of organizing pneumonia Respiratory Medicine Case Reports |
| title | Cryptococcosis as a cause of organizing pneumonia |
| title_full | Cryptococcosis as a cause of organizing pneumonia |
| title_fullStr | Cryptococcosis as a cause of organizing pneumonia |
| title_full_unstemmed | Cryptococcosis as a cause of organizing pneumonia |
| title_short | Cryptococcosis as a cause of organizing pneumonia |
| title_sort | cryptococcosis as a cause of organizing pneumonia |
| url | http://www.sciencedirect.com/science/article/pii/S2213007119301029 |
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