Protective effect of low-dose risedronate against osteocyte apoptosis and bone loss in ovariectomized rats.

Osteocyte apoptosis is the first reaction to estrogen depletion, thereby stimulating osteoclastic bone resorption resulting in bone loss. We investigated the effects of two different risedronate (RIS) doses (high and low) on osteocyte apoptosis, osteoclast activity and bone loss in ovariectomized ra...

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Autori principali: Tingjun Ye, Peng Cao, Jin Qi, Qi Zhou, D Sudhaker Rao, Shijing Qiu
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2017-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC5646759?pdf=render