Current perspectives on the immunosuppressive tumor microenvironment in hepatocellular carcinoma: challenges and opportunities

Current perspectives on the immunosuppressive tumor microenvironment in hepatocellular carcinoma: challenges and opportunities

Abstract Incidence of hepatocellular carcinoma (HCC) is on the rise due to the prevalence of chronic hepatitis and cirrhosis. Although there are surgical and chemotherapy treatment avenues the mortality rate of HCC remains high. Immunotherapy is currently the new frontier of cancer treatment and the...

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Bibliographic Details
Main Authors: Chen Lu, Dawei Rong, Betty Zhang, Wubin Zheng, Xuehao Wang, Ziyi Chen, Weiwei Tang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Molecular Cancer
Subjects:
Hepatocellular carcinoma
Macrophages
Myeloid suppressor cells
Immunotherapy
Online Access:http://link.springer.com/article/10.1186/s12943-019-1047-6

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