Cyclin-dependent kinase 7/9 inhibitor SNS-032 induces apoptosis in diffuse large B-cell lymphoma cells

Cyclin-dependent kinase 7/9 inhibitor SNS-032 induces apoptosis in diffuse large B-cell lymphoma cells

Approximately 40% of patients with diffuse large B-cell lymphoma (DLBCL) are refractory or relapse to standard chemotherapy, and most of them are activated B cell-like DLBCLs (ABC-DLBCL) and germinal center B cell-like DLBCLs (GCB-DLBCL). SNS-032, a novel and selective CDK7/9 inhibitor, that the fir...

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Bibliographic Details
Main Authors: Liling Jiang, Chuangyu Wen, Huan Zhou, Aochu Liu, Haichuan Zhang, Xinmei Chen, Wa Ding, Jinbao Liu, Xianping Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Cancer Biology & Therapy
Subjects:
sns-032
apoptosis
diffuse large b-cell lymphoma
chemotherapy
cyclin-dependent kinase 7/9
Online Access:http://dx.doi.org/10.1080/15384047.2022.2055421

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