Fungal infections in humans: the silent crisis

Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on the rise with a number of social and medical developments during the past decades that have abetted the spread of fungal...

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Main Authors: Katharina Kainz, Maria A. Bauer, Frank Madeo, Didac Carmona-Gutierrez
Format: Article
Language:English
Published: Shared Science Publishers OG 2020-06-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/2020a-kainz-microbial-cell/
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author Katharina Kainz
Maria A. Bauer
Frank Madeo
Didac Carmona-Gutierrez
author_facet Katharina Kainz
Maria A. Bauer
Frank Madeo
Didac Carmona-Gutierrez
author_sort Katharina Kainz
collection DOAJ
description Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on the rise with a number of social and medical developments during the past decades that have abetted the spread of fungal infections. Additionally, the long-term therapeutic application and prophylactic use of antifungal drugs in high-risk patients have promoted the emergence of (multi)drug-resistant fungi, including the extremely virulent strain Candida auris. Hence, fungal infections are already a global threat that is becoming increasingly severe. In this article, we underline the importance of more and effective research to counteract fungal infections and their consequences.
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spelling doaj.art-2335978da9114cf9a655fdcf7592dde22022-12-22T01:55:02ZengShared Science Publishers OGMicrobial Cell2311-26382020-06-017614314510.15698/mic2020.06.718Fungal infections in humans: the silent crisisKatharina Kainz0Maria A. Bauer1Frank Madeo2Didac Carmona-Gutierrez3Institute for Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.Institute for Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.Institute for Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.Institute for Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on the rise with a number of social and medical developments during the past decades that have abetted the spread of fungal infections. Additionally, the long-term therapeutic application and prophylactic use of antifungal drugs in high-risk patients have promoted the emergence of (multi)drug-resistant fungi, including the extremely virulent strain Candida auris. Hence, fungal infections are already a global threat that is becoming increasingly severe. In this article, we underline the importance of more and effective research to counteract fungal infections and their consequences.http://microbialcell.com/researcharticles/2020a-kainz-microbial-cell/candidaresistanceantifungalsyeastantimycoticsdrugazoles
spellingShingle Katharina Kainz
Maria A. Bauer
Frank Madeo
Didac Carmona-Gutierrez
Fungal infections in humans: the silent crisis
Microbial Cell
candida
resistance
antifungals
yeast
antimycotics
drug
azoles
title Fungal infections in humans: the silent crisis
title_full Fungal infections in humans: the silent crisis
title_fullStr Fungal infections in humans: the silent crisis
title_full_unstemmed Fungal infections in humans: the silent crisis
title_short Fungal infections in humans: the silent crisis
title_sort fungal infections in humans the silent crisis
topic candida
resistance
antifungals
yeast
antimycotics
drug
azoles
url http://microbialcell.com/researcharticles/2020a-kainz-microbial-cell/
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AT didaccarmonagutierrez fungalinfectionsinhumansthesilentcrisis