HMGA2 as a Critical Regulator in Cancer Development

HMGA2 as a Critical Regulator in Cancer Development

The high mobility group protein 2 (HMGA2) regulates gene expression by binding to AT-rich regions of DNA. Akin to other DNA architectural proteins, HMGA2 is highly expressed in embryonic stem cells during embryogenesis, while its expression is more limited at later stages of development and in adult...

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Bibliographic Details
Main Authors: Behzad Mansoori, Ali Mohammadi, Henrik J. Ditzel, Pascal H. G. Duijf, Vahid Khaze, Morten F. Gjerstorff, Behzad Baradaran
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Genes
Subjects:
HMGA2
cancer
cell cycle
apoptosis
DNA repair
MAPK
Online Access:https://www.mdpi.com/2073-4425/12/2/269

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