Metformin reverse minocycline to inhibit minocycline-resistant Acinetobacter baumannii by destroy the outer membrane and enhance membrane potential in vitro

Metformin reverse minocycline to inhibit minocycline-resistant Acinetobacter baumannii by destroy the outer membrane and enhance membrane potential in vitro

Abstract Background Acinetobacter baumannii (A. baumannii) is an opportunistic pathogen and has emerged as one of the most troublesome pathogens. Drug resistance in A. baumannii has been reported on a global scale. Minocycline was found to be active against multi-drug resistant A. baumannii and was...

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Bibliographic Details
Main Authors: Tingting Guo, Xiaoli Sun, Jie Yang, Liying Yang, Mengying Li, Yuhang Wang, Hongmei Jiao, Guocai Li
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Microbiology
Subjects:
Acinetobacter baumannii
Metformin
Minocycline
Potentiator
Mechanisms
Online Access:https://doi.org/10.1186/s12866-022-02629-4

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