Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages

Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages

Infections with viral pathogens are widespread and can cause a variety of different diseases. In-depth knowledge about viral triggers initiating an immune response is necessary to decipher viral pathogenesis. Inflammasomes, as part of the innate immune system, can be activated by viral pathogens. Ho...

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Bibliographic Details
Main Authors: Hannah S. Eisfeld, Alexander Simonis, Sandra Winter, Jason Chhen, Luisa J. Ströh, Thomas Krey, Manuel Koch, Sebastian J. Theobald, Jan Rybniker
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Viruses
Subjects:
NLRP3
IL-1β
pyroptosis
viral glycoproteins
innate immunity
macrophages
Online Access:https://www.mdpi.com/1999-4915/13/10/2076

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