OPA1 supports mitochondrial dynamics and immune evasion to CD8+ T cell in lung adenocarcinoma

OPA1 supports mitochondrial dynamics and immune evasion to CD8+ T cell in lung adenocarcinoma

Background Mitochondrial fusion and fission were identified to play key roles during multiple biology process. Thus, we aim to investigate the roles of OPA1 in mitochondria fusion and immune evasion of non-small cell lung cancer cells. Methods The transcriptional activation of genes related to mitoc...

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Bibliographic Details
Main Authors: Ying Wang, Yadong Li, Xuanwei Jiang, Yayun Gu, Hui Zheng, Xiaoxuan Wang, Haotian Zhang, Jixiang Wu, Yang Cheng
Format: Article
Language:English
Published: PeerJ Inc. 2022-12-01
Series:PeerJ
Subjects:
OPA1
Lung adenocarcinoma
Mitochondrial fusion
Immune evasion
CD8+ T cell
Online Access:https://peerj.com/articles/14543.pdf

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