Vitamin D levels in pregnancies and neonatal outcomes
Objective: We aimed to evaluate the differences in obstetrics and neonatal outcomes, such as mode of delivery, gestational diabetes mellitus, preeclampsia, and infant birth weight between pregnancies with normal and insufficient vitamin D levels. Methods: The study was designed as a retrosp...
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| Format: | Article |
| Language: | English |
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Perinatal Medicine Foundation
2023-04-01
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| Series: | Perinatal Journal |
| Online Access: | https://www.perinataljournal.com/Archive/Article/20230311005 |
| _version_ | 1797852494137655296 |
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| author | Bilge Keskinsoy Bengü Mutlu Sütçüoğlu Halis Özdemir Merih Bayram |
| author_facet | Bilge Keskinsoy Bengü Mutlu Sütçüoğlu Halis Özdemir Merih Bayram |
| author_sort | Bilge Keskinsoy |
| collection | DOAJ |
| description | Objective: We aimed to evaluate the differences in obstetrics and neonatal outcomes, such as mode of delivery, gestational diabetes mellitus, preeclampsia, and infant birth weight between pregnancies with normal and insufficient vitamin D levels. Methods: The study was designed as a retrospective study. One hundred and seventy-nine pregnant women who were followed up at our clinic and whose vitamin D levels were evaluated in each trimester were included. All patients were administered 1200 IU/day beginning from the 12 weeks of gestation in accordance with the national guidelines. Vitamin D levels above 20 ng/ml were defined as sufficient, and those below 20 ng/ml were defined as insufficient. Results: The median vitamin D level in the third trimester was significantly higher than that in the first and second trimesters (p<0.001). There was a moderate positive correlation between vitamin D levels in infant cord blood at the time of birth and vitamin D levels in the third trimester (p<0.001, R=0.496). Birth weights of the patients with insufficient vitamin D levels in the first trimester but with sufficient neonatal cord blood levels as a result of treatment were significantly higher compared to those in patients with insufficient cord blood vitamin D levels (3327 g vs. 3133 g, p=0.030). Conclusion: This study observed that neonatal cord blood vitamin D level is a better indicator than antenatal vitamin D levels. Regardless of first-trimester vitamin D levels, infant birth weights were significantly higher in the group with sufficient neonatal cord blood levels. |
| first_indexed | 2024-04-09T19:35:15Z |
| format | Article |
| id | doaj.art-2341f46c11104c248cc5444f3eb80b54 |
| institution | Directory Open Access Journal |
| issn | 1305-3124 |
| language | English |
| last_indexed | 2024-04-09T19:35:15Z |
| publishDate | 2023-04-01 |
| publisher | Perinatal Medicine Foundation |
| record_format | Article |
| series | Perinatal Journal |
| spelling | doaj.art-2341f46c11104c248cc5444f3eb80b542023-04-04T12:49:28ZengPerinatal Medicine FoundationPerinatal Journal1305-31242023-04-01311253010.2399/prn.23.0311005Vitamin D levels in pregnancies and neonatal outcomesBilge Keskinsoyhttps://orcid.org/0000-0002-4309-6538Bengü Mutlu Sütçüoğluhttps://orcid.org/0000-0002-5594-1719Halis Özdemirhttps://orcid.org/0000-0002-9194-8504Merih Bayramhttps://orcid.org/0000-0003-1299-2433 Objective: We aimed to evaluate the differences in obstetrics and neonatal outcomes, such as mode of delivery, gestational diabetes mellitus, preeclampsia, and infant birth weight between pregnancies with normal and insufficient vitamin D levels. Methods: The study was designed as a retrospective study. One hundred and seventy-nine pregnant women who were followed up at our clinic and whose vitamin D levels were evaluated in each trimester were included. All patients were administered 1200 IU/day beginning from the 12 weeks of gestation in accordance with the national guidelines. Vitamin D levels above 20 ng/ml were defined as sufficient, and those below 20 ng/ml were defined as insufficient. Results: The median vitamin D level in the third trimester was significantly higher than that in the first and second trimesters (p<0.001). There was a moderate positive correlation between vitamin D levels in infant cord blood at the time of birth and vitamin D levels in the third trimester (p<0.001, R=0.496). Birth weights of the patients with insufficient vitamin D levels in the first trimester but with sufficient neonatal cord blood levels as a result of treatment were significantly higher compared to those in patients with insufficient cord blood vitamin D levels (3327 g vs. 3133 g, p=0.030). Conclusion: This study observed that neonatal cord blood vitamin D level is a better indicator than antenatal vitamin D levels. Regardless of first-trimester vitamin D levels, infant birth weights were significantly higher in the group with sufficient neonatal cord blood levels.https://www.perinataljournal.com/Archive/Article/20230311005 |
| spellingShingle | Bilge Keskinsoy Bengü Mutlu Sütçüoğlu Halis Özdemir Merih Bayram Vitamin D levels in pregnancies and neonatal outcomes Perinatal Journal |
| title | Vitamin D levels in pregnancies and neonatal outcomes |
| title_full | Vitamin D levels in pregnancies and neonatal outcomes |
| title_fullStr | Vitamin D levels in pregnancies and neonatal outcomes |
| title_full_unstemmed | Vitamin D levels in pregnancies and neonatal outcomes |
| title_short | Vitamin D levels in pregnancies and neonatal outcomes |
| title_sort | vitamin d levels in pregnancies and neonatal outcomes |
| url | https://www.perinataljournal.com/Archive/Article/20230311005 |
| work_keys_str_mv | AT bilgekeskinsoy vitamindlevelsinpregnanciesandneonataloutcomes AT bengumutlusutcuoglu vitamindlevelsinpregnanciesandneonataloutcomes AT halisozdemir vitamindlevelsinpregnanciesandneonataloutcomes AT merihbayram vitamindlevelsinpregnanciesandneonataloutcomes |