A Case of Frequent Arousal Following Nocturnal Dyspnea Caused by Gastroesophageal Reflux Disease

Gastroesophageal reflux disease (GERD) is a common disorder that is associated with many esophageal syndromes and complications. Most cases of reflux event occur during the day, but reflux during sleep can cause not only esophageal problems, but also sleep problems, such as arousal and poor sleep qu...

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Main Authors: Dae Wui Yoon, Seung Ku Lee, Jin Kwan Kim, Chang-Ho Yun, Chol Shin
Format: Article
Language:English
Published: Korean Society of Sleep Medicine 2013-06-01
Series:Sleep Medicine Research
Subjects:
Online Access:http://www.sleepmedres.org/upload/pdf/smr-4-1-33.pdf
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author Dae Wui Yoon
Seung Ku Lee
Jin Kwan Kim
Chang-Ho Yun
Chol Shin
author_facet Dae Wui Yoon
Seung Ku Lee
Jin Kwan Kim
Chang-Ho Yun
Chol Shin
author_sort Dae Wui Yoon
collection DOAJ
description Gastroesophageal reflux disease (GERD) is a common disorder that is associated with many esophageal syndromes and complications. Most cases of reflux event occur during the day, but reflux during sleep can cause not only esophageal problems, but also sleep problems, such as arousal and poor sleep quality. We report the case of a 17-year-old man who had been referred to us with frequent arousal following sudden dyspnea. On polysomnography, no respiratory disturbances and periodic limb movements were found during the sleep study, but frequent events of arousal were reported (arousal index: 12.3/h). On a 24-hr esophageal pH monitoring test, his DeMeester score was 176.43 and the total reflux time was 1120.9 min (76.9%), indicating the presence of significant acid reflux. After treatment with a proton-pump inhibitor, the arousals following nocturnal dyspnea and fatigue in the morning disappeared in the patient. GERD should be considered as a cause of spontaneous arousal or awakening not accompanying respiratory disturbances.
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spelling doaj.art-2342e4ce66044882b9c29b0e7d6c81492022-12-22T01:52:44ZengKorean Society of Sleep MedicineSleep Medicine Research2093-91752233-88532013-06-0141333510.17241/smr.2013.4.1.3337A Case of Frequent Arousal Following Nocturnal Dyspnea Caused by Gastroesophageal Reflux DiseaseDae Wui Yoon0Seung Ku Lee1Jin Kwan Kim2Chang-Ho Yun3Chol Shin4 Institute of Human Genomic Study, Ansan Hospital, College of Medicine, Korea University, Ansan, Korea Institute of Human Genomic Study, Ansan Hospital, College of Medicine, Korea University, Ansan, Korea Department of Biomedical Laboratory Science, Jungwon University, Goesan, Korea Department of Neurology and Clinical Neuroscience Center, Seoul National University Bundang Hospital, College of Medicine, Seoul National University, Seongnam, Korea Institute of Human Genomic Study, Ansan Hospital, College of Medicine, Korea University, Ansan, KoreaGastroesophageal reflux disease (GERD) is a common disorder that is associated with many esophageal syndromes and complications. Most cases of reflux event occur during the day, but reflux during sleep can cause not only esophageal problems, but also sleep problems, such as arousal and poor sleep quality. We report the case of a 17-year-old man who had been referred to us with frequent arousal following sudden dyspnea. On polysomnography, no respiratory disturbances and periodic limb movements were found during the sleep study, but frequent events of arousal were reported (arousal index: 12.3/h). On a 24-hr esophageal pH monitoring test, his DeMeester score was 176.43 and the total reflux time was 1120.9 min (76.9%), indicating the presence of significant acid reflux. After treatment with a proton-pump inhibitor, the arousals following nocturnal dyspnea and fatigue in the morning disappeared in the patient. GERD should be considered as a cause of spontaneous arousal or awakening not accompanying respiratory disturbances.http://www.sleepmedres.org/upload/pdf/smr-4-1-33.pdfGastroesophageal reflux diseaseArousalDyspneaDeMeester
spellingShingle Dae Wui Yoon
Seung Ku Lee
Jin Kwan Kim
Chang-Ho Yun
Chol Shin
A Case of Frequent Arousal Following Nocturnal Dyspnea Caused by Gastroesophageal Reflux Disease
Sleep Medicine Research
Gastroesophageal reflux disease
Arousal
Dyspnea
DeMeester
title A Case of Frequent Arousal Following Nocturnal Dyspnea Caused by Gastroesophageal Reflux Disease
title_full A Case of Frequent Arousal Following Nocturnal Dyspnea Caused by Gastroesophageal Reflux Disease
title_fullStr A Case of Frequent Arousal Following Nocturnal Dyspnea Caused by Gastroesophageal Reflux Disease
title_full_unstemmed A Case of Frequent Arousal Following Nocturnal Dyspnea Caused by Gastroesophageal Reflux Disease
title_short A Case of Frequent Arousal Following Nocturnal Dyspnea Caused by Gastroesophageal Reflux Disease
title_sort case of frequent arousal following nocturnal dyspnea caused by gastroesophageal reflux disease
topic Gastroesophageal reflux disease
Arousal
Dyspnea
DeMeester
url http://www.sleepmedres.org/upload/pdf/smr-4-1-33.pdf
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