Efficient estimation for large-scale linkage disequilibrium patterns of the human genome
In this study, we proposed an efficient algorithm (X-LD) for estimating linkage disequilibrium (LD) patterns for a genomic grid, which can be of inter-chromosomal scale or of small segments. Compared with conventional methods, the proposed method was significantly faster, dropped from O(nm2) to O(n2...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/90636 |