Efficient estimation for large-scale linkage disequilibrium patterns of the human genome

Efficient estimation for large-scale linkage disequilibrium patterns of the human genome

In this study, we proposed an efficient algorithm (X-LD) for estimating linkage disequilibrium (LD) patterns for a genomic grid, which can be of inter-chromosomal scale or of small segments. Compared with conventional methods, the proposed method was significantly faster, dropped from O(nm2) to O(n2...

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Bibliographic Details
Main Authors: Xin Huang, Tian-Neng Zhu, Ying-Chao Liu, Guo-An Qi, Jian-Nan Zhang, Guo-Bo Chen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-12-01
Series:eLife
Subjects:
linkage disequilibrium pattern
inter-chromosome
efficient algorithm
Online Access:https://elifesciences.org/articles/90636

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