Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological ally
Hyperferritinemic syndrome represents a common nosological classification for systemic inflammatory syndromes, including Catastrophic antiphospholipid syndrome, in which hyperferritinemia (> 500 ng/mL) is present. Recent studies suggest that in this syndrome, ferritin is more than a passive marke...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2023-06-01
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| Series: | Romanian Journal of Rheumatology |
| Subjects: | |
| Online Access: | https://rjr.com.ro/articles/2023.2/RJR_2023_2_Art-06.pdf |
| _version_ | 1827386457887604736 |
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| author | Andrei Blanaru Mara Adelina Benchea Doina Nitescu Iulia Diana Florescu Razvan Adrian Ionescu |
| author_facet | Andrei Blanaru Mara Adelina Benchea Doina Nitescu Iulia Diana Florescu Razvan Adrian Ionescu |
| author_sort | Andrei Blanaru |
| collection | DOAJ |
| description | Hyperferritinemic syndrome represents a common nosological classification for systemic inflammatory syndromes, including Catastrophic antiphospholipid syndrome, in which hyperferritinemia (> 500 ng/mL) is present. Recent studies suggest that in this syndrome, ferritin is more than a passive marker of inflammation, playing an active role in the process.
We present the case of a 74-year-old female patient with elevated serum ferritin levels (above 1000 ng/mL), along with an intense inflammatory syndrome, non-immune thrombotic microangiopathy, and multisystem involvement (pulmonary, cardiac, hepatic, pancreatic, neurological and renal changes), outlining the picture of a hyperferritinemic syndrome that is hard to classify otherwise. This underlines the necessity for diagnostic and classification criteria for this pathology. |
| first_indexed | 2024-03-08T15:45:33Z |
| format | Article |
| id | doaj.art-2344095e7ca7463fa410e75cdf2b7339 |
| institution | Directory Open Access Journal |
| issn | 1843-0791 2069-6086 |
| language | English |
| last_indexed | 2024-03-08T15:45:33Z |
| publishDate | 2023-06-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Rheumatology |
| spelling | doaj.art-2344095e7ca7463fa410e75cdf2b73392024-01-09T11:09:42ZengAmaltea Medical Publishing HouseRomanian Journal of Rheumatology1843-07912069-60862023-06-01322768510.37897/RJR.2023.2.6Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological allyAndrei Blanaru0Mara Adelina Benchea1Doina Nitescu2Iulia Diana Florescu3Razvan Adrian Ionescu43rd Internal Medicine Department, Colentina Clinical Hospital, Bucharest, Romania 3rd Internal Medicine Department, Colentina Clinical Hospital, Bucharest, Romania 3rd Internal Medicine Department, Colentina Clinical Hospital, Bucharest, Romania 1st Nephrology Department, Hospital of Nephrology “Dr. Carol Davila”, Bucharest, Romania3rd Internal Medicine Department, Colentina Clinical Hospital, Bucharest, Romania; 2 “Carol Davila”, University of Medicine and Pharmacy, Bucharest, RomaniaHyperferritinemic syndrome represents a common nosological classification for systemic inflammatory syndromes, including Catastrophic antiphospholipid syndrome, in which hyperferritinemia (> 500 ng/mL) is present. Recent studies suggest that in this syndrome, ferritin is more than a passive marker of inflammation, playing an active role in the process. We present the case of a 74-year-old female patient with elevated serum ferritin levels (above 1000 ng/mL), along with an intense inflammatory syndrome, non-immune thrombotic microangiopathy, and multisystem involvement (pulmonary, cardiac, hepatic, pancreatic, neurological and renal changes), outlining the picture of a hyperferritinemic syndrome that is hard to classify otherwise. This underlines the necessity for diagnostic and classification criteria for this pathology.https://rjr.com.ro/articles/2023.2/RJR_2023_2_Art-06.pdfhyperferritinemic syndromecatastrophic antiphospholipid syndrome (caps) |
| spellingShingle | Andrei Blanaru Mara Adelina Benchea Doina Nitescu Iulia Diana Florescu Razvan Adrian Ionescu Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological ally Romanian Journal of Rheumatology hyperferritinemic syndrome catastrophic antiphospholipid syndrome (caps) |
| title | Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological ally |
| title_full | Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological ally |
| title_fullStr | Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological ally |
| title_full_unstemmed | Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological ally |
| title_short | Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological ally |
| title_sort | antiphospholipid syndrome ferritin and fever hyperferritinemic syndrome a nosological ally |
| topic | hyperferritinemic syndrome catastrophic antiphospholipid syndrome (caps) |
| url | https://rjr.com.ro/articles/2023.2/RJR_2023_2_Art-06.pdf |
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