Determination and comparison of mechanical properties of articular cartilage using pro-hyper-viscoelastic models based on an unconfined stress relaxation
Recently, the most common tool to compensate for various organ defects is tissue transplantation with several problems involved. These problems have led to the rapid growth of tissue engineering with a designed tissue approach or organ substitute in the last decade. For this purpose, it is important...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Semnan University
2021-09-01
|
| Series: | مجله مدل سازی در مهندسی |
| Subjects: | |
| Online Access: | https://modelling.semnan.ac.ir/article_5566_f58d1ba10c96c44e13035036d4efb23d.pdf |
| _version_ | 1797296519604338688 |
|---|---|
| author | reza balali dehkordi alireza seifzadeh Fatemeh Farhatnia Ali Mokhtarian |
| author_facet | reza balali dehkordi alireza seifzadeh Fatemeh Farhatnia Ali Mokhtarian |
| author_sort | reza balali dehkordi |
| collection | DOAJ |
| description | Recently, the most common tool to compensate for various organ defects is tissue transplantation with several problems involved. These problems have led to the rapid growth of tissue engineering with a designed tissue approach or organ substitute in the last decade. For this purpose, it is important to determine the tissue mechanical properties. In this study, to obtain the cartilage structural parameters, isotropic Pro-Hyper-Viscoelastic Mooney-Rivlin and Neo-Hooke are used. These model coefficients are obtained by reverse engineering methods and using a coupled finite element-optimization algorithm utilized unconfined stress relaxation tests with root-mean-square error (RMSE)) less than 0.036, 0.033 for Neo-Hooke and Mooney-Rivlin respectively. Using Neo-Hooke and Mooney-Rivlin models, the modulus of elasticity was 0.47 MPa and 0.44 MPa, and the shear modulus was 0.188 MPa and 0.184 MPa, respectively. The predicted tissue mechanical response obtained by the finite element model showed that the Mooney-Rivlin model is more consistent with the stress relaxation experiments than Neo-Hooke one. The results showed that during the stress relaxation test, by applying a compressing load on the sample, initially the fluid pressurization in the matrix pores has the most contribution in the load-bearing (total stress). When time elapses, the fluid contribution in the load-bearing decreases, and the solid matrix contribution increases. |
| first_indexed | 2024-03-07T22:05:56Z |
| format | Article |
| id | doaj.art-23457338e5fd4d81a260b5d5e91d23a5 |
| institution | Directory Open Access Journal |
| issn | 2008-4854 2783-2538 |
| language | fas |
| last_indexed | 2024-03-07T22:05:56Z |
| publishDate | 2021-09-01 |
| publisher | Semnan University |
| record_format | Article |
| series | مجله مدل سازی در مهندسی |
| spelling | doaj.art-23457338e5fd4d81a260b5d5e91d23a52024-02-23T19:08:53ZfasSemnan Universityمجله مدل سازی در مهندسی2008-48542783-25382021-09-0119669510610.22075/jme.2021.22688.20485566Determination and comparison of mechanical properties of articular cartilage using pro-hyper-viscoelastic models based on an unconfined stress relaxationreza balali dehkordi0alireza seifzadeh1Fatemeh Farhatnia2Ali Mokhtarian3Islamic Azad UniversityDepartment of Biomedical Engineering, Khomeinishahr Branch, Islamic Azad University, Khomeinishahr/Isfahan, IranIslamic Azad UniversityIslamic Azad UniversityRecently, the most common tool to compensate for various organ defects is tissue transplantation with several problems involved. These problems have led to the rapid growth of tissue engineering with a designed tissue approach or organ substitute in the last decade. For this purpose, it is important to determine the tissue mechanical properties. In this study, to obtain the cartilage structural parameters, isotropic Pro-Hyper-Viscoelastic Mooney-Rivlin and Neo-Hooke are used. These model coefficients are obtained by reverse engineering methods and using a coupled finite element-optimization algorithm utilized unconfined stress relaxation tests with root-mean-square error (RMSE)) less than 0.036, 0.033 for Neo-Hooke and Mooney-Rivlin respectively. Using Neo-Hooke and Mooney-Rivlin models, the modulus of elasticity was 0.47 MPa and 0.44 MPa, and the shear modulus was 0.188 MPa and 0.184 MPa, respectively. The predicted tissue mechanical response obtained by the finite element model showed that the Mooney-Rivlin model is more consistent with the stress relaxation experiments than Neo-Hooke one. The results showed that during the stress relaxation test, by applying a compressing load on the sample, initially the fluid pressurization in the matrix pores has the most contribution in the load-bearing (total stress). When time elapses, the fluid contribution in the load-bearing decreases, and the solid matrix contribution increases.https://modelling.semnan.ac.ir/article_5566_f58d1ba10c96c44e13035036d4efb23d.pdfarticular cartilagestress relaxationoptimization algorithmviscoelasticfinite elementpro-hyper-viscoelastic |
| spellingShingle | reza balali dehkordi alireza seifzadeh Fatemeh Farhatnia Ali Mokhtarian Determination and comparison of mechanical properties of articular cartilage using pro-hyper-viscoelastic models based on an unconfined stress relaxation مجله مدل سازی در مهندسی articular cartilage stress relaxation optimization algorithm viscoelastic finite element pro-hyper-viscoelastic |
| title | Determination and comparison of mechanical properties of articular cartilage using pro-hyper-viscoelastic models based on an unconfined stress relaxation |
| title_full | Determination and comparison of mechanical properties of articular cartilage using pro-hyper-viscoelastic models based on an unconfined stress relaxation |
| title_fullStr | Determination and comparison of mechanical properties of articular cartilage using pro-hyper-viscoelastic models based on an unconfined stress relaxation |
| title_full_unstemmed | Determination and comparison of mechanical properties of articular cartilage using pro-hyper-viscoelastic models based on an unconfined stress relaxation |
| title_short | Determination and comparison of mechanical properties of articular cartilage using pro-hyper-viscoelastic models based on an unconfined stress relaxation |
| title_sort | determination and comparison of mechanical properties of articular cartilage using pro hyper viscoelastic models based on an unconfined stress relaxation |
| topic | articular cartilage stress relaxation optimization algorithm viscoelastic finite element pro-hyper-viscoelastic |
| url | https://modelling.semnan.ac.ir/article_5566_f58d1ba10c96c44e13035036d4efb23d.pdf |
| work_keys_str_mv | AT rezabalalidehkordi determinationandcomparisonofmechanicalpropertiesofarticularcartilageusingprohyperviscoelasticmodelsbasedonanunconfinedstressrelaxation AT alirezaseifzadeh determinationandcomparisonofmechanicalpropertiesofarticularcartilageusingprohyperviscoelasticmodelsbasedonanunconfinedstressrelaxation AT fatemehfarhatnia determinationandcomparisonofmechanicalpropertiesofarticularcartilageusingprohyperviscoelasticmodelsbasedonanunconfinedstressrelaxation AT alimokhtarian determinationandcomparisonofmechanicalpropertiesofarticularcartilageusingprohyperviscoelasticmodelsbasedonanunconfinedstressrelaxation |