Increased multiple sclerosis relapses related to lower prevalence of pain
Objective The study aims to investigate the presence of pain amongst multiple sclerosis (MS) patients. Method One hundred MS patients responded to questionnaires evaluating neuropathic and nociceptive pain, depression and anxiety. Statistical analysis was performed using the Mann–Whitney U, Chi-Squa...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
2015-07-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000700593&lng=en&tlng=en |
| _version_ | 1811339053720666112 |
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| author | José Vinícius Martins da Silva Beatriz Fátima Alves de Oliveira Osvaldo José Moreira do Nascimento João Gabriel Dib Farinhas Maria Graziella Cavaliere Henrique de Sá Rodrigues Cal André Palma da Cunha Matta |
| author_facet | José Vinícius Martins da Silva Beatriz Fátima Alves de Oliveira Osvaldo José Moreira do Nascimento João Gabriel Dib Farinhas Maria Graziella Cavaliere Henrique de Sá Rodrigues Cal André Palma da Cunha Matta |
| author_sort | José Vinícius Martins da Silva |
| collection | DOAJ |
| description | Objective The study aims to investigate the presence of pain amongst multiple sclerosis (MS) patients. Method One hundred MS patients responded to questionnaires evaluating neuropathic and nociceptive pain, depression and anxiety. Statistical analysis was performed using the Mann–Whitney U, Chi-Square and two-tailed Fisher’s exact tests and multivariate logistic regression. Results Women had a statistically higher prevalence of pain (p = 0.037), and chances of having pain after the age of 50 reduced. Women with pain had a statistically significant lower number of relapses (p = 0.003), restricting analysis to those patients with more than one relapse. After the second relapse, each relapse reduced the chance of having pain by 46%. Presence of pain was independent of Expanded Disability Status Scale (EDSS) anxiety, and depression. Conclusion Our findings suggest a strong inverse association between relapses and pain indicating a possible protective role of focal inflammation in the control of pain. |
| first_indexed | 2024-04-13T18:20:22Z |
| format | Article |
| id | doaj.art-2345fe86be434518a3edbd096f555692 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-04-13T18:20:22Z |
| publishDate | 2015-07-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-2345fe86be434518a3edbd096f5556922022-12-22T02:35:29ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272015-07-0173759360010.1590/0004-282X20150073S0004-282X2015000700593Increased multiple sclerosis relapses related to lower prevalence of painJosé Vinícius Martins da SilvaBeatriz Fátima Alves de OliveiraOsvaldo José Moreira do NascimentoJoão Gabriel Dib FarinhasMaria Graziella CavaliereHenrique de Sá Rodrigues CalAndré Palma da Cunha MattaObjective The study aims to investigate the presence of pain amongst multiple sclerosis (MS) patients. Method One hundred MS patients responded to questionnaires evaluating neuropathic and nociceptive pain, depression and anxiety. Statistical analysis was performed using the Mann–Whitney U, Chi-Square and two-tailed Fisher’s exact tests and multivariate logistic regression. Results Women had a statistically higher prevalence of pain (p = 0.037), and chances of having pain after the age of 50 reduced. Women with pain had a statistically significant lower number of relapses (p = 0.003), restricting analysis to those patients with more than one relapse. After the second relapse, each relapse reduced the chance of having pain by 46%. Presence of pain was independent of Expanded Disability Status Scale (EDSS) anxiety, and depression. Conclusion Our findings suggest a strong inverse association between relapses and pain indicating a possible protective role of focal inflammation in the control of pain.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000700593&lng=en&tlng=enesclerose múltipladorprevalênciasurtosexo |
| spellingShingle | José Vinícius Martins da Silva Beatriz Fátima Alves de Oliveira Osvaldo José Moreira do Nascimento João Gabriel Dib Farinhas Maria Graziella Cavaliere Henrique de Sá Rodrigues Cal André Palma da Cunha Matta Increased multiple sclerosis relapses related to lower prevalence of pain Arquivos de Neuro-Psiquiatria esclerose múltipla dor prevalência surto sexo |
| title | Increased multiple sclerosis relapses related to lower prevalence of pain |
| title_full | Increased multiple sclerosis relapses related to lower prevalence of pain |
| title_fullStr | Increased multiple sclerosis relapses related to lower prevalence of pain |
| title_full_unstemmed | Increased multiple sclerosis relapses related to lower prevalence of pain |
| title_short | Increased multiple sclerosis relapses related to lower prevalence of pain |
| title_sort | increased multiple sclerosis relapses related to lower prevalence of pain |
| topic | esclerose múltipla dor prevalência surto sexo |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000700593&lng=en&tlng=en |
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