Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains

Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains

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Cerebral organoids show great promise as tools to unravel the complex mechanisms by which the mammalian brain develops during embryogenesis. We generated mouse cerebral organoids harbouring constitutive or conditional mutations in Pax6, which encodes a transcription factor with multiple important ro...

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Bibliographic Details
Main Authors: Nurfarhana Ferdaos, Sally Lowell, John O. Mason
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704552/?tool=EBI

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