Chordin-like 2 influences the differentiation fate of retinal pigment epithelium cells by dynamically regulating BMP pathway

Chordin-like 2 influences the differentiation fate of retinal pigment epithelium cells by dynamically regulating BMP pathway

AIM: To explore the functions of Chordin-like 2, which is encoded by CHRDL2, in the process of retinal pigmented epithelium (RPE) differentiation and damage repair. METHODS: The fetal RPE cells (fRPE) was obtained from aborted fetus which obeyed medical ethics. Real-time quantitative polymerase chai...

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Bibliographic Details
Main Authors: Duo Li, Song-Tao Yuan, Xin-Yi Xie, Han Shen, Qing-Huai Liu, Yong Yao
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2022-05-01
Series:International Journal of Ophthalmology
Subjects:
retinal pigmented epithelium differentiation
epithelial-mesenchymal transition
bmp pathway
cell proliferation
Online Access:http://ies.ijo.cn/en_publish/2022/5/20220504.pdf

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