Collagen supplementation in skin and orthopedic diseases: A review of the literature
Collagen is one of the main components of the extracellular matrix of the dermis and articular cartilage and influences the body’s mechanical, organizational, and tissue formation properties. Produced from food industry by-products, it is considered a nutraceutical product widely used as an ingredie...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-04-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023021680 |
| _version_ | 1797837004968296448 |
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| author | Luana Dias Campos Valfredo de Almeida Santos Junior Júlia Demuner Pimentel Gabriel Lusi Fernandes Carregã Cinthia Baú Betim Cazarin |
| author_facet | Luana Dias Campos Valfredo de Almeida Santos Junior Júlia Demuner Pimentel Gabriel Lusi Fernandes Carregã Cinthia Baú Betim Cazarin |
| author_sort | Luana Dias Campos |
| collection | DOAJ |
| description | Collagen is one of the main components of the extracellular matrix of the dermis and articular cartilage and influences the body’s mechanical, organizational, and tissue formation properties. Produced from food industry by-products, it is considered a nutraceutical product widely used as an ingredient or supplement in food, pharmaceutical, and cosmetic industries. This study aimed to conduct a literature review on the scientific evidence regarding the beneficial effects of collagen consumption in the treatment of skin and orthopedic diseases. Literature data have shown that hydrolyzed collagen supplementation promotes skin changes, such as decreased wrinkle formation; increased skin elasticity; increased hydration; increased collagen content, density, and synthesis, which are factors closely associated with aging-related skin damage. Regarding orthopedic changes, collagen supplementation increases bone strength, density, and mass; improves joint stiffness/mobility, and functionality; and reduces pain. These aspects are associated with bone loss due to aging and damage caused by strenuous physical activity. Thus, this review addresses the economic and health potential of this source of amino acids and bioactive peptides extracted from food industry by-products. |
| first_indexed | 2024-04-09T15:17:57Z |
| format | Article |
| id | doaj.art-234bcf2a4db24783a3afd941b1a9efbc |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-09T15:17:57Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-234bcf2a4db24783a3afd941b1a9efbc2023-04-29T14:52:15ZengElsevierHeliyon2405-84402023-04-0194e14961Collagen supplementation in skin and orthopedic diseases: A review of the literatureLuana Dias Campos0Valfredo de Almeida Santos Junior1Júlia Demuner Pimentel2Gabriel Lusi Fernandes Carregã3Cinthia Baú Betim Cazarin4Universidade Estadual de Campinas, School of Food Engineering, Department of Food Science and Nutrition, Rua Monteiro Lobato, 80, 13083-862, Campinas, SP, BrazilUniversidade Estadual de Campinas, School of Food Engineering, Department of Food Science and Nutrition, Rua Monteiro Lobato, 80, 13083-862, Campinas, SP, BrazilUniversidade Vila Velha, Avenida Comissário José Dantas de Melo, 21, Boa Vista II, 29102-920, Vila Velha, ES, BrazilUniversidade Estadual de Campinas (UNICAMP), School of Physical Education, Campinas, São Paulo, BrazilUniversidade Estadual de Campinas, School of Food Engineering, Department of Food Science and Nutrition, Rua Monteiro Lobato, 80, 13083-862, Campinas, SP, Brazil; Corresponding author.Collagen is one of the main components of the extracellular matrix of the dermis and articular cartilage and influences the body’s mechanical, organizational, and tissue formation properties. Produced from food industry by-products, it is considered a nutraceutical product widely used as an ingredient or supplement in food, pharmaceutical, and cosmetic industries. This study aimed to conduct a literature review on the scientific evidence regarding the beneficial effects of collagen consumption in the treatment of skin and orthopedic diseases. Literature data have shown that hydrolyzed collagen supplementation promotes skin changes, such as decreased wrinkle formation; increased skin elasticity; increased hydration; increased collagen content, density, and synthesis, which are factors closely associated with aging-related skin damage. Regarding orthopedic changes, collagen supplementation increases bone strength, density, and mass; improves joint stiffness/mobility, and functionality; and reduces pain. These aspects are associated with bone loss due to aging and damage caused by strenuous physical activity. Thus, this review addresses the economic and health potential of this source of amino acids and bioactive peptides extracted from food industry by-products.http://www.sciencedirect.com/science/article/pii/S2405844023021680SkinJointBone metabolismSenescenceAging |
| spellingShingle | Luana Dias Campos Valfredo de Almeida Santos Junior Júlia Demuner Pimentel Gabriel Lusi Fernandes Carregã Cinthia Baú Betim Cazarin Collagen supplementation in skin and orthopedic diseases: A review of the literature Heliyon Skin Joint Bone metabolism Senescence Aging |
| title | Collagen supplementation in skin and orthopedic diseases: A review of the literature |
| title_full | Collagen supplementation in skin and orthopedic diseases: A review of the literature |
| title_fullStr | Collagen supplementation in skin and orthopedic diseases: A review of the literature |
| title_full_unstemmed | Collagen supplementation in skin and orthopedic diseases: A review of the literature |
| title_short | Collagen supplementation in skin and orthopedic diseases: A review of the literature |
| title_sort | collagen supplementation in skin and orthopedic diseases a review of the literature |
| topic | Skin Joint Bone metabolism Senescence Aging |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023021680 |
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