Role for HIF-1α and Downstream Pathways in Regulating Neuronal Injury after Intracerebral Hemorrhage in Diabetes

Role for HIF-1α and Downstream Pathways in Regulating Neuronal Injury after Intracerebral Hemorrhage in Diabetes

Background/Aims: HIF-1α is accumulated in the cellular nucleus and cytoplasm under conditions of oxygen deprivation and engaged in pathophysiologic changes of homeostasis by modulating the expression of several target genes. As an endogenous signaling protein, HIF-1α contributes to in neuroprotectio...

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Bibliographic Details
Main Authors: Zhen Yu, Ling Tang, Lifen Chen, Jinfang Li, Wanfu Wu, Changlin Hu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Intracerebral hemorrhage
HIF-1α
VEGF
Diabetes
Online Access:http://www.karger.com/Article/FullText/430334

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