In‐depth proteomics characterization of ∆Np73 effectors identifies key proteins with diagnostic potential implicated in lymphangiogenesis, vasculogenesis and metastasis in colorectal cancer

In‐depth proteomics characterization of ∆Np73 effectors identifies key proteins with diagnostic potential implicated in lymphangiogenesis, vasculogenesis and metastasis in colorectal cancer

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer‐related death worldwide. Alterations in proteins of the p53‐family are a common event in CRC. ΔNp73, a p53‐family member, shows oncogenic properties and its effectors are largely unknown. We performed an i...

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Bibliographic Details
Main Authors: María Garranzo‐Asensio, Javier Rodríguez‐Cobos, Coral San Millán, Carmen Poves, María Jesús Fernández‐Aceñero, Daniel Pastor‐Morate, David Viñal, Ana Montero‐Calle, Guillermo Solís‐Fernández, María‐Ángeles Ceron, Manuel Gámez‐Chiachio, Nuria Rodríguez, Ana Guzmán‐Aránguez, Rodrigo Barderas, Gemma Domínguez
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Molecular Oncology
Subjects:
∆Np73 effectors
colorectal cancer
in‐depth proteomics
lymphangiogenesis
secretome
Online Access:https://doi.org/10.1002/1878-0261.13228

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