Exploiting Viscoelastic Experimental Observations and Numerical Simulations to Infer Biomimetic Artificial Tendon Fiber Designs
Designing biomimetic artificial tendons requires a thorough, data-based understanding of the tendon's inner material properties. The current work exploits viscoelastic experimental observations at the tendon fascicle scale, making use of mechanical and data analysis methods. More specifically,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-05-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2019.00085/full |
| _version_ | 1819156304610983936 |
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| author | Nikolaos Karathanasopoulos Jean-Francois Ganghoffer |
| author_facet | Nikolaos Karathanasopoulos Jean-Francois Ganghoffer |
| author_sort | Nikolaos Karathanasopoulos |
| collection | DOAJ |
| description | Designing biomimetic artificial tendons requires a thorough, data-based understanding of the tendon's inner material properties. The current work exploits viscoelastic experimental observations at the tendon fascicle scale, making use of mechanical and data analysis methods. More specifically, based on reported elastic, volumetric and relaxation fascicle scale properties, we infer most probable, mechanically compatible material attributes at the fiber scale. In particular, the work provides pairs of elastic and viscous fiber-scale moduli, which can reproduce the upper scale tendon mechanics. The computed range of values for the fiber-scale tendon viscosity attest to the substantial stress relaxation capabilities of tendons. More importantly, the reported mechanical parameters constitute a basis for the design of tendon-specific restoration materials, such as fiber-based, engineering scaffolds. |
| first_indexed | 2024-12-22T15:50:45Z |
| format | Article |
| id | doaj.art-23503550b19e4b948ad1396bef4f4564 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-22T15:50:45Z |
| publishDate | 2019-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-23503550b19e4b948ad1396bef4f45642022-12-21T18:20:55ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852019-05-01710.3389/fbioe.2019.00085449073Exploiting Viscoelastic Experimental Observations and Numerical Simulations to Infer Biomimetic Artificial Tendon Fiber DesignsNikolaos Karathanasopoulos0Jean-Francois Ganghoffer1Chair of Computational Modeling of Materials in Manufacturing, ETH Zürich, Zurich, SwitzerlandLEM3, CNRS, University of Lorraine, Metz, FranceDesigning biomimetic artificial tendons requires a thorough, data-based understanding of the tendon's inner material properties. The current work exploits viscoelastic experimental observations at the tendon fascicle scale, making use of mechanical and data analysis methods. More specifically, based on reported elastic, volumetric and relaxation fascicle scale properties, we infer most probable, mechanically compatible material attributes at the fiber scale. In particular, the work provides pairs of elastic and viscous fiber-scale moduli, which can reproduce the upper scale tendon mechanics. The computed range of values for the fiber-scale tendon viscosity attest to the substantial stress relaxation capabilities of tendons. More importantly, the reported mechanical parameters constitute a basis for the design of tendon-specific restoration materials, such as fiber-based, engineering scaffolds.https://www.frontiersin.org/article/10.3389/fbioe.2019.00085/fulltendontissue engineeringbiomaterialsviscoelasticityfibersrelaxation |
| spellingShingle | Nikolaos Karathanasopoulos Jean-Francois Ganghoffer Exploiting Viscoelastic Experimental Observations and Numerical Simulations to Infer Biomimetic Artificial Tendon Fiber Designs Frontiers in Bioengineering and Biotechnology tendon tissue engineering biomaterials viscoelasticity fibers relaxation |
| title | Exploiting Viscoelastic Experimental Observations and Numerical Simulations to Infer Biomimetic Artificial Tendon Fiber Designs |
| title_full | Exploiting Viscoelastic Experimental Observations and Numerical Simulations to Infer Biomimetic Artificial Tendon Fiber Designs |
| title_fullStr | Exploiting Viscoelastic Experimental Observations and Numerical Simulations to Infer Biomimetic Artificial Tendon Fiber Designs |
| title_full_unstemmed | Exploiting Viscoelastic Experimental Observations and Numerical Simulations to Infer Biomimetic Artificial Tendon Fiber Designs |
| title_short | Exploiting Viscoelastic Experimental Observations and Numerical Simulations to Infer Biomimetic Artificial Tendon Fiber Designs |
| title_sort | exploiting viscoelastic experimental observations and numerical simulations to infer biomimetic artificial tendon fiber designs |
| topic | tendon tissue engineering biomaterials viscoelasticity fibers relaxation |
| url | https://www.frontiersin.org/article/10.3389/fbioe.2019.00085/full |
| work_keys_str_mv | AT nikolaoskarathanasopoulos exploitingviscoelasticexperimentalobservationsandnumericalsimulationstoinferbiomimeticartificialtendonfiberdesigns AT jeanfrancoisganghoffer exploitingviscoelasticexperimentalobservationsandnumericalsimulationstoinferbiomimeticartificialtendonfiberdesigns |