Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency department
IntroductionGeriatric syndrome (GS) increases risk of disability and mortality in older adults. Sarcopenia is a predominant illness of GS and accelerate its progression. This study aimed to investigate associations between mortality, emergency department (ED) re-visits and GS-related illnesses among...
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.1027503/full |
| _version_ | 1797956152935317504 |
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| author | Mei-Chen Liao Cheng-Chang Yen Yuh-Te Lin Yuh-Te Lin Fong-Dee Huang Yun-Te Chang Yun-Te Chang Yun-Te Chang Yun-Te Chang |
| author_facet | Mei-Chen Liao Cheng-Chang Yen Yuh-Te Lin Yuh-Te Lin Fong-Dee Huang Yun-Te Chang Yun-Te Chang Yun-Te Chang Yun-Te Chang |
| author_sort | Mei-Chen Liao |
| collection | DOAJ |
| description | IntroductionGeriatric syndrome (GS) increases risk of disability and mortality in older adults. Sarcopenia is a predominant illness of GS and accelerate its progression. This study aimed to investigate associations between mortality, emergency department (ED) re-visits and GS-related illnesses among older adults who visited the ED.MethodThis retrospective observational study enrolled elderly patients who visited the ED in our hospital between January 2018 and October 2020. Patients were evaluated for potential sarcopenia, which was defined by both low handgrip strength and calf circumference. Follow-up was at least 6 months. Data of age, gender, mortality, ED re-visits, and GS-related illnesses were collected and analyzed for associations.ResultsA total of 273 older adults aged 74 years or older were included, of whom 194 were diagnosed with possible sarcopenia. Older adults with possible sarcopenia also had significantly lower body mass index (BMI); a higher proportion needed assistance with daily activities; more had malnutrition, frailty, and history of falls (all p < 0.001) and acute decline in activities of daily living (p = 0.027). Multivariate analysis showed that possible sarcopenia [adjusted hazard ratio, aHR): 9.89, 95% confidence interval (CI): 1.17–83.81, p = 0.036], living in residential institutions (aHR: 2.85, 95% CI: 1.08–7.50, p = 0.034), and frailty (aHR: 7.30, 95% CI: 1.20–44.62, p = 0.031) were associated with mortality. Aged over 85 years (adjusted odds ratio: 2.44, 95% CI: 1.25–4.80, p = 0.02) was associated with ED re-visits.ConclusionSarcopenia is associated with mortality among older adults who visit ED. Initial screening for sarcopenia and relevant risk factors among older adults in the ED may help with early intervention for those at high-risk and may improve their prognosis. |
| first_indexed | 2024-04-10T23:44:26Z |
| format | Article |
| id | doaj.art-23512acf6e2242149cd47f0fc363aa26 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T23:44:26Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-23512acf6e2242149cd47f0fc363aa262023-01-11T05:07:10ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-01-01910.3389/fmed.2022.10275031027503Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency departmentMei-Chen Liao0Cheng-Chang Yen1Yuh-Te Lin2Yuh-Te Lin3Fong-Dee Huang4Yun-Te Chang5Yun-Te Chang6Yun-Te Chang7Yun-Te Chang8Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung City, TaiwanDivision of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City, TaiwanCenter for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung City, TaiwanDivision of Neurology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City, TaiwanDepartment of Emergency Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City, TaiwanDepartment of Emergency Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City, TaiwanSchool of Medicine, National Yang-Ming University, Taipei City, TaiwanDepartment of Physical Therapy, Shu-Zen Junior College of Medicine and Management, Kaohsiung City, TaiwanDepartment of Emergency & Critical Care Medicine, Pingtung Veterans General Hospital, Pingtung City, TaiwanIntroductionGeriatric syndrome (GS) increases risk of disability and mortality in older adults. Sarcopenia is a predominant illness of GS and accelerate its progression. This study aimed to investigate associations between mortality, emergency department (ED) re-visits and GS-related illnesses among older adults who visited the ED.MethodThis retrospective observational study enrolled elderly patients who visited the ED in our hospital between January 2018 and October 2020. Patients were evaluated for potential sarcopenia, which was defined by both low handgrip strength and calf circumference. Follow-up was at least 6 months. Data of age, gender, mortality, ED re-visits, and GS-related illnesses were collected and analyzed for associations.ResultsA total of 273 older adults aged 74 years or older were included, of whom 194 were diagnosed with possible sarcopenia. Older adults with possible sarcopenia also had significantly lower body mass index (BMI); a higher proportion needed assistance with daily activities; more had malnutrition, frailty, and history of falls (all p < 0.001) and acute decline in activities of daily living (p = 0.027). Multivariate analysis showed that possible sarcopenia [adjusted hazard ratio, aHR): 9.89, 95% confidence interval (CI): 1.17–83.81, p = 0.036], living in residential institutions (aHR: 2.85, 95% CI: 1.08–7.50, p = 0.034), and frailty (aHR: 7.30, 95% CI: 1.20–44.62, p = 0.031) were associated with mortality. Aged over 85 years (adjusted odds ratio: 2.44, 95% CI: 1.25–4.80, p = 0.02) was associated with ED re-visits.ConclusionSarcopenia is associated with mortality among older adults who visit ED. Initial screening for sarcopenia and relevant risk factors among older adults in the ED may help with early intervention for those at high-risk and may improve their prognosis.https://www.frontiersin.org/articles/10.3389/fmed.2022.1027503/fullsarcopeniageriatric syndromesystemic inflammationelderly emergencyprognosis |
| spellingShingle | Mei-Chen Liao Cheng-Chang Yen Yuh-Te Lin Yuh-Te Lin Fong-Dee Huang Yun-Te Chang Yun-Te Chang Yun-Te Chang Yun-Te Chang Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency department Frontiers in Medicine sarcopenia geriatric syndrome systemic inflammation elderly emergency prognosis |
| title | Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency department |
| title_full | Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency department |
| title_fullStr | Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency department |
| title_full_unstemmed | Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency department |
| title_short | Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency department |
| title_sort | sarcopenia is associated with mortality in non critical elderly patients visiting the emergency department |
| topic | sarcopenia geriatric syndrome systemic inflammation elderly emergency prognosis |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.1027503/full |
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