Expression and significance of histone H3K27 demethylases in renal cell carcinoma

Expression and significance of histone H3K27 demethylases in renal cell carcinoma

<p>Abstract</p> <p>Background</p> <p>The histone H3K27 demethylases UTX and JMJD3 are important regulatory factors that modulate gene expression by altering the physical state of chromatin. Previous studies have indicated an abnormal H3K27 methylation status in carcinog...

Full description

Bibliographic Details
Main Authors: Shen Yongqing, Guo Xiaoqiang, Wang Yuejia, Qiu Wei, Chang Yanzhong, Zhang Aili, Duan Xianglin
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Cancer
Subjects:
Renal cell carcinoma
Histone H3K27 demethylase
UTX
JMJD3
Epigenetics
Online Access:http://www.biomedcentral.com/1471-2407/12/470

Similar Items

Similar Items