Alternative ATPase domain interactions in eukaryotic Hsp70 chaperones

Alternative ATPase domain interactions in eukaryotic Hsp70 chaperones

Hsp70 molecular chaperones are essential components for maintaining protein homeostasis within cells. They interact with substrate or client proteins in a well characterised fashion that is regulated by ATP and supported by co-chaperones. In eukaryotes there is a vast array of Hsp70 isoforms that ma...

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Bibliographic Details
Main Authors: Yassin Ben-Khoud, Chao-Sheng Chen, Maruf M. U. Ali
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Hsp70
eukaryotic chaperones
BiP
IRE1
Tim44
XIAP
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1155784/full

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