Wnt/beta-catenin pathway: modulating anticancer immune response

Wnt/beta-catenin pathway: modulating anticancer immune response

Abstract Wnt/β-catenin signaling, a highly conserved pathway through evolution, regulates key cellular functions including proliferation, differentiation, migration, genetic stability, apoptosis, and stem cell renewal. The Wnt pathway mediates biological processes by a canonical or noncanonical path...

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Bibliographic Details
Main Authors: Sachin Gopalkrishna Pai, Benedito A. Carneiro, Jose Mauricio Mota, Ricardo Costa, Caio Abner Leite, Romualdo Barroso-Sousa, Jason Benjamin Kaplan, Young Kwang Chae, Francis Joseph Giles
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Hematology & Oncology
Subjects:
Wnt
β-catenin
Immunotherapy
Cancer immune regulation
Immune exclusion
Online Access:http://link.springer.com/article/10.1186/s13045-017-0471-6

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