Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

<p>Abstract</p> <p>Background</p> <p>Age-related cognitive dysfunction, including impairment of hippocampus-dependent spatial learning and memory, affects approximately half of the aged population. Induction of a variety of neuroinflammatory measures has been reported w...

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Bibliographic Details
Main Authors: Sonntag William E, Warrington Junie P, Yan Han, Farley Julie A, Brucklacher Robert M, Bixler Georgina V, VanGuilder Heather D, Freeman Willard M
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Neuroinflammation
Subjects:
hippocampus
cognitive decline
para-inflammation
neuroinflammation
aging
Morris water maze
Online Access:http://www.jneuroinflammation.com/content/8/1/138

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