Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response

Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response

Complete and accurate DNA replication is essential to genome stability maintenance during cellular division. However, cells are routinely challenged by endogenous as well as exogenous agents that threaten DNA stability. DNA breaks and the activation of the DNA damage response (DDR) arising from endo...

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Bibliographic Details
Main Authors: Sandrine Ragu, Gabriel Matos-Rodrigues, Bernard S. Lopez
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
DNA damage response
replicative stress
DNA repair
innate immunity
inflammation
cGAS-STING
Online Access:https://www.mdpi.com/2073-4425/11/4/409

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