Shiga Toxin-Producing <i>Escherichia coli</i> and Milk Fat Globules
Shiga toxin-producing <i>Escherichia coli</i> (STEC) are zoonotic Gram-negative bacteria. While raw milk cheese consumption is healthful, contamination with pathogens such as STEC can occur due to poor hygiene practices at the farm level. STEC infections cause mild to serious symptoms in...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-02-01
|
| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/10/3/496 |
| _version_ | 1827627516014100480 |
|---|---|
| author | Arthur Bagel Delphine Sergentet |
| author_facet | Arthur Bagel Delphine Sergentet |
| author_sort | Arthur Bagel |
| collection | DOAJ |
| description | Shiga toxin-producing <i>Escherichia coli</i> (STEC) are zoonotic Gram-negative bacteria. While raw milk cheese consumption is healthful, contamination with pathogens such as STEC can occur due to poor hygiene practices at the farm level. STEC infections cause mild to serious symptoms in humans. The raw milk cheese-making process concentrates certain milk macromolecules such as proteins and milk fat globules (MFGs), allowing the intrinsic beneficial and pathogenic microflora to continue to thrive. MFGs are surrounded by a biological membrane, the milk fat globule membrane (MFGM), which has a globally positive health effect, including inhibition of pathogen adhesion. In this review, we provide an update on the adhesion between STEC and raw MFGs and highlight the consequences of this interaction in terms of food safety, pathogen detection, and therapeutic development. |
| first_indexed | 2024-03-09T13:16:11Z |
| format | Article |
| id | doaj.art-236aff538ffb499ca8e572ed14c505a3 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-09T13:16:11Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-236aff538ffb499ca8e572ed14c505a32023-11-30T21:35:05ZengMDPI AGMicroorganisms2076-26072022-02-0110349610.3390/microorganisms10030496Shiga Toxin-Producing <i>Escherichia coli</i> and Milk Fat GlobulesArthur Bagel0Delphine Sergentet1‘Bacterial Opportunistic Pathogens and Environment’ Research Team, Université de Lyon, UMR5557 Ecologie Microbienne Lyon, CNRS (National Center of Scientific Research), VetAgro Sup, Marcy-l’Etoile, 69280 Lyon, France‘Bacterial Opportunistic Pathogens and Environment’ Research Team, Université de Lyon, UMR5557 Ecologie Microbienne Lyon, CNRS (National Center of Scientific Research), VetAgro Sup, Marcy-l’Etoile, 69280 Lyon, FranceShiga toxin-producing <i>Escherichia coli</i> (STEC) are zoonotic Gram-negative bacteria. While raw milk cheese consumption is healthful, contamination with pathogens such as STEC can occur due to poor hygiene practices at the farm level. STEC infections cause mild to serious symptoms in humans. The raw milk cheese-making process concentrates certain milk macromolecules such as proteins and milk fat globules (MFGs), allowing the intrinsic beneficial and pathogenic microflora to continue to thrive. MFGs are surrounded by a biological membrane, the milk fat globule membrane (MFGM), which has a globally positive health effect, including inhibition of pathogen adhesion. In this review, we provide an update on the adhesion between STEC and raw MFGs and highlight the consequences of this interaction in terms of food safety, pathogen detection, and therapeutic development.https://www.mdpi.com/2076-2607/10/3/496STECMFGMraw milk cheeseanti-adhesion strategy |
| spellingShingle | Arthur Bagel Delphine Sergentet Shiga Toxin-Producing <i>Escherichia coli</i> and Milk Fat Globules Microorganisms STEC MFGM raw milk cheese anti-adhesion strategy |
| title | Shiga Toxin-Producing <i>Escherichia coli</i> and Milk Fat Globules |
| title_full | Shiga Toxin-Producing <i>Escherichia coli</i> and Milk Fat Globules |
| title_fullStr | Shiga Toxin-Producing <i>Escherichia coli</i> and Milk Fat Globules |
| title_full_unstemmed | Shiga Toxin-Producing <i>Escherichia coli</i> and Milk Fat Globules |
| title_short | Shiga Toxin-Producing <i>Escherichia coli</i> and Milk Fat Globules |
| title_sort | shiga toxin producing i escherichia coli i and milk fat globules |
| topic | STEC MFGM raw milk cheese anti-adhesion strategy |
| url | https://www.mdpi.com/2076-2607/10/3/496 |
| work_keys_str_mv | AT arthurbagel shigatoxinproducingiescherichiacoliiandmilkfatglobules AT delphinesergentet shigatoxinproducingiescherichiacoliiandmilkfatglobules |