Scientific Opinion on the safety and efficacy of Phyzyme XP (6‐phytase) as a feed additive for minor poultry species

Abstract Phyzyme XP is a feed additive that contains 6‐phytase, produced by a genetically modified strain of Schizosaccharomyces pombe (ATCC 5233) and is authorised for use in feed for chickens and turkeys for fattening, laying hens, ducks, piglets, pigs for fattening and sows. The applicant request...

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Main Author: EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Format: Article
Language:English
Published: Wiley 2012-03-01
Series:EFSA Journal
Subjects:
Online Access:https://doi.org/10.2903/j.efsa.2012.2619
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author EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
author_facet EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
author_sort EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
collection DOAJ
description Abstract Phyzyme XP is a feed additive that contains 6‐phytase, produced by a genetically modified strain of Schizosaccharomyces pombe (ATCC 5233) and is authorised for use in feed for chickens and turkeys for fattening, laying hens, ducks, piglets, pigs for fattening and sows. The applicant requested for an extension of use of the additive to all minor poultry species. Safety for chickens and turkeys for fattening and for laying hens was previously established at 750, 1000 and 1500 U/kg feed, respectively. Given the margin of safety established for the major poultry species, a maximum dose of 1000 U/kg feed was considered safe for all minor poultry species. Since the mode of action of phytases can be reasonably assumed to be the same in all avian species the minimum effective dose authorised for fattening birds (250 U/kg feed) and for laying birds (150 U/kg feed) was considered efficacious for minor poultry species.
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spelling doaj.art-236b2cd1c28a40089ac133138584aa952022-12-21T22:25:21ZengWileyEFSA Journal1831-47322012-03-01103n/an/a10.2903/j.efsa.2012.2619Scientific Opinion on the safety and efficacy of Phyzyme XP (6‐phytase) as a feed additive for minor poultry speciesEFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Abstract Phyzyme XP is a feed additive that contains 6‐phytase, produced by a genetically modified strain of Schizosaccharomyces pombe (ATCC 5233) and is authorised for use in feed for chickens and turkeys for fattening, laying hens, ducks, piglets, pigs for fattening and sows. The applicant requested for an extension of use of the additive to all minor poultry species. Safety for chickens and turkeys for fattening and for laying hens was previously established at 750, 1000 and 1500 U/kg feed, respectively. Given the margin of safety established for the major poultry species, a maximum dose of 1000 U/kg feed was considered safe for all minor poultry species. Since the mode of action of phytases can be reasonably assumed to be the same in all avian species the minimum effective dose authorised for fattening birds (250 U/kg feed) and for laying birds (150 U/kg feed) was considered efficacious for minor poultry species.https://doi.org/10.2903/j.efsa.2012.2619Enzymezootechnical additivedigestibility enhancersminor poultry speciesphytasesafety
spellingShingle EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Scientific Opinion on the safety and efficacy of Phyzyme XP (6‐phytase) as a feed additive for minor poultry species
EFSA Journal
Enzyme
zootechnical additive
digestibility enhancers
minor poultry species
phytase
safety
title Scientific Opinion on the safety and efficacy of Phyzyme XP (6‐phytase) as a feed additive for minor poultry species
title_full Scientific Opinion on the safety and efficacy of Phyzyme XP (6‐phytase) as a feed additive for minor poultry species
title_fullStr Scientific Opinion on the safety and efficacy of Phyzyme XP (6‐phytase) as a feed additive for minor poultry species
title_full_unstemmed Scientific Opinion on the safety and efficacy of Phyzyme XP (6‐phytase) as a feed additive for minor poultry species
title_short Scientific Opinion on the safety and efficacy of Phyzyme XP (6‐phytase) as a feed additive for minor poultry species
title_sort scientific opinion on the safety and efficacy of phyzyme xp 6 phytase as a feed additive for minor poultry species
topic Enzyme
zootechnical additive
digestibility enhancers
minor poultry species
phytase
safety
url https://doi.org/10.2903/j.efsa.2012.2619
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