A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis

Abstract Background Hemolytic streptococcus gangrene is a life threatening invasive bacterial infection. Hemolytic streptococcus gangrene in the danger triangle of the face is too lethal to operate. A case of the confirmed hemolytic streptococcus gangrene in the danger triangle of the face caused by...

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Main Authors: Xiao-ling Jia, Janak L. Pathak, Jin-fa Tong, Ji-mei Su
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Pediatrics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12887-018-1177-9
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author Xiao-ling Jia
Janak L. Pathak
Jin-fa Tong
Ji-mei Su
author_facet Xiao-ling Jia
Janak L. Pathak
Jin-fa Tong
Ji-mei Su
author_sort Xiao-ling Jia
collection DOAJ
description Abstract Background Hemolytic streptococcus gangrene is a life threatening invasive bacterial infection. Hemolytic streptococcus gangrene in the danger triangle of the face is too lethal to operate. A case of the confirmed hemolytic streptococcus gangrene in the danger triangle of the face caused by Group A beta-hemolytic streptococcus (GAS) in 20-months old boy is presented to draw attention of clinicians to this uncommon but frequently fatal infection. Case presentation Previously healthy 20 months old boy suddenly developed paranasal gangrene on the left side of the danger triangle of the face, followed by rapidly progressive thrombocytopenia and hepatitis. The clinical features, liver function, and hematological and serological parameters resembled to a description of streptococcal toxic shock syndrome (STSS). Aggressive antibiotics, substitutional and supportive therapy were conducted without surgical debridement of facial tissues. Prompt diagnosis and aggressive timely treatment completely cured the disease in 28 days. Conclusions The present case report demonstrates prompt diagnosis and timely treatment as a strategy to cure the fatal hemolytic streptococcus gangrene located in too risky body part to operate.
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spelling doaj.art-236bc6f74c9a409c9e96041c92d603c82022-12-22T00:34:23ZengBMCBMC Pediatrics1471-24312018-06-011811510.1186/s12887-018-1177-9A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitisXiao-ling Jia0Janak L. Pathak1Jin-fa Tong2Ji-mei Su3Department of Stomatology, Hangzhou Hospital of Traditional Chinese MedicineKey Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatological Hospital of Guangzhou Medical UniversityDepartment of Stomatology, Hangzhou Hospital of Traditional Chinese MedicineDepartment of Stomatology, Children’s Hospital, Zhejiang University School of MedicineAbstract Background Hemolytic streptococcus gangrene is a life threatening invasive bacterial infection. Hemolytic streptococcus gangrene in the danger triangle of the face is too lethal to operate. A case of the confirmed hemolytic streptococcus gangrene in the danger triangle of the face caused by Group A beta-hemolytic streptococcus (GAS) in 20-months old boy is presented to draw attention of clinicians to this uncommon but frequently fatal infection. Case presentation Previously healthy 20 months old boy suddenly developed paranasal gangrene on the left side of the danger triangle of the face, followed by rapidly progressive thrombocytopenia and hepatitis. The clinical features, liver function, and hematological and serological parameters resembled to a description of streptococcal toxic shock syndrome (STSS). Aggressive antibiotics, substitutional and supportive therapy were conducted without surgical debridement of facial tissues. Prompt diagnosis and aggressive timely treatment completely cured the disease in 28 days. Conclusions The present case report demonstrates prompt diagnosis and timely treatment as a strategy to cure the fatal hemolytic streptococcus gangrene located in too risky body part to operate.http://link.springer.com/article/10.1186/s12887-018-1177-9Hemolytic streptococcus gangreneGroup-a beta-hemolytic streptococcusThe danger triangle of the faceThrombocytopeniaHepatitis
spellingShingle Xiao-ling Jia
Janak L. Pathak
Jin-fa Tong
Ji-mei Su
A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis
BMC Pediatrics
Hemolytic streptococcus gangrene
Group-a beta-hemolytic streptococcus
The danger triangle of the face
Thrombocytopenia
Hepatitis
title A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis
title_full A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis
title_fullStr A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis
title_full_unstemmed A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis
title_short A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis
title_sort case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis
topic Hemolytic streptococcus gangrene
Group-a beta-hemolytic streptococcus
The danger triangle of the face
Thrombocytopenia
Hepatitis
url http://link.springer.com/article/10.1186/s12887-018-1177-9
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