Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience
Objective To report our experience with management of fetuses with congenital high airway obstruction syndrome (CHAOS). Methods We retrospectively reviewed the cases of fetuses who were prenatally diagnosed and postnatally confirmed with CHAOS between 2010 and 2019 at Asan Medical Center, Seoul, Kor...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Obstetrics and Gynecology
2021-01-01
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| Series: | Obstetrics & Gynecology Science |
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| Online Access: | http://www.ogscience.org/upload/pdf/ogs-20266.pdf |
| _version_ | 1818657002630414336 |
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| author | Sang-Hee Jeong Mi-Young Lee Ok-Ju Kang Rina Kim Jin-Hoon Chung Hye-Sung Won Pil-Ryang Lee Euiseok Jung Byong Sop Lee Woo-Jong Choi Yoon Se Lee |
| author_facet | Sang-Hee Jeong Mi-Young Lee Ok-Ju Kang Rina Kim Jin-Hoon Chung Hye-Sung Won Pil-Ryang Lee Euiseok Jung Byong Sop Lee Woo-Jong Choi Yoon Se Lee |
| author_sort | Sang-Hee Jeong |
| collection | DOAJ |
| description | Objective To report our experience with management of fetuses with congenital high airway obstruction syndrome (CHAOS). Methods We retrospectively reviewed the cases of fetuses who were prenatally diagnosed and postnatally confirmed with CHAOS between 2010 and 2019 at Asan Medical Center, Seoul, Korea. Results Of 13 fetuses prenatally diagnosed with CHAOS, 7 were lost to follow-up and 6 were postnatally confirmed as having CHAOS. All fetuses, except one were delivered via cesarean section with an ex utero intrapartum treatment (EXIT) procedure. Two patients had coexisting congenital heart diseases requiring several cardiac surgeries following birth. Both of these patients demonstrated developmental delay; however, the remaining 4 had a normal development except for expressive language. Two infants died of respiratory complications, and the remaining 4 were alive at the end of the follow-up period. All 4 live patients underwent tracheostomy with planned reconstruction surgery. Three children are now able to phonate, and 1 can maintain a conservation. Conclusion The proper management of CHAOS using the EXIT procedure results in high survival and low hypoxemia-induced complication rates. Therefore, an accurate prenatal diagnosis is necessary for an appropriate perinatal management. |
| first_indexed | 2024-12-17T03:34:33Z |
| format | Article |
| id | doaj.art-236c974a2a6f4da5a761cf03feba3c64 |
| institution | Directory Open Access Journal |
| issn | 2287-8572 2287-8580 |
| language | English |
| last_indexed | 2024-12-17T03:34:33Z |
| publishDate | 2021-01-01 |
| publisher | Korean Society of Obstetrics and Gynecology |
| record_format | Article |
| series | Obstetrics & Gynecology Science |
| spelling | doaj.art-236c974a2a6f4da5a761cf03feba3c642022-12-21T22:05:09ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802021-01-01641526110.5468/ogs.202668597Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experienceSang-Hee Jeong0Mi-Young Lee1Ok-Ju Kang2Rina Kim3Jin-Hoon Chung4Hye-Sung Won5Pil-Ryang Lee6Euiseok Jung7Byong Sop Lee8Woo-Jong Choi9Yoon Se Lee10 Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Division of Neonatology, Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Division of Neonatology, Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Departments of Anaesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaObjective To report our experience with management of fetuses with congenital high airway obstruction syndrome (CHAOS). Methods We retrospectively reviewed the cases of fetuses who were prenatally diagnosed and postnatally confirmed with CHAOS between 2010 and 2019 at Asan Medical Center, Seoul, Korea. Results Of 13 fetuses prenatally diagnosed with CHAOS, 7 were lost to follow-up and 6 were postnatally confirmed as having CHAOS. All fetuses, except one were delivered via cesarean section with an ex utero intrapartum treatment (EXIT) procedure. Two patients had coexisting congenital heart diseases requiring several cardiac surgeries following birth. Both of these patients demonstrated developmental delay; however, the remaining 4 had a normal development except for expressive language. Two infants died of respiratory complications, and the remaining 4 were alive at the end of the follow-up period. All 4 live patients underwent tracheostomy with planned reconstruction surgery. Three children are now able to phonate, and 1 can maintain a conservation. Conclusion The proper management of CHAOS using the EXIT procedure results in high survival and low hypoxemia-induced complication rates. Therefore, an accurate prenatal diagnosis is necessary for an appropriate perinatal management.http://www.ogscience.org/upload/pdf/ogs-20266.pdfairway obstructionlaryngeal diseaseprenatal diagnosistracheostomy |
| spellingShingle | Sang-Hee Jeong Mi-Young Lee Ok-Ju Kang Rina Kim Jin-Hoon Chung Hye-Sung Won Pil-Ryang Lee Euiseok Jung Byong Sop Lee Woo-Jong Choi Yoon Se Lee Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience Obstetrics & Gynecology Science airway obstruction laryngeal disease prenatal diagnosis tracheostomy |
| title | Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience |
| title_full | Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience |
| title_fullStr | Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience |
| title_full_unstemmed | Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience |
| title_short | Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience |
| title_sort | perinatal outcome of fetuses with congenital high airway obstruction syndrome a single center experience |
| topic | airway obstruction laryngeal disease prenatal diagnosis tracheostomy |
| url | http://www.ogscience.org/upload/pdf/ogs-20266.pdf |
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