The lymphatic system in alcohol-associated liver disease

The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic live...

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Main Authors: Reiichiro Kondo, Yasuko Iwakiri
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2020-10-01
Series:Clinical and Molecular Hepatology
Subjects:
Online Access:http://e-cmh.org/upload/pdf/cmh-2020-0179.pdf
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author Reiichiro Kondo
Yasuko Iwakiri
author_facet Reiichiro Kondo
Yasuko Iwakiri
author_sort Reiichiro Kondo
collection DOAJ
description The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.
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spelling doaj.art-236da85be71a4fb79a413181047684ec2022-12-21T23:39:07ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2020-10-0126463363810.3350/cmh.2020.01791539The lymphatic system in alcohol-associated liver diseaseReiichiro Kondo0Yasuko Iwakiri1 Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USAThe lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.http://e-cmh.org/upload/pdf/cmh-2020-0179.pdflymphangiogenesisvascular endothelial growth factor cinflammationlymphatics
spellingShingle Reiichiro Kondo
Yasuko Iwakiri
The lymphatic system in alcohol-associated liver disease
Clinical and Molecular Hepatology
lymphangiogenesis
vascular endothelial growth factor c
inflammation
lymphatics
title The lymphatic system in alcohol-associated liver disease
title_full The lymphatic system in alcohol-associated liver disease
title_fullStr The lymphatic system in alcohol-associated liver disease
title_full_unstemmed The lymphatic system in alcohol-associated liver disease
title_short The lymphatic system in alcohol-associated liver disease
title_sort lymphatic system in alcohol associated liver disease
topic lymphangiogenesis
vascular endothelial growth factor c
inflammation
lymphatics
url http://e-cmh.org/upload/pdf/cmh-2020-0179.pdf
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AT yasukoiwakiri thelymphaticsysteminalcoholassociatedliverdisease
AT reiichirokondo lymphaticsysteminalcoholassociatedliverdisease
AT yasukoiwakiri lymphaticsysteminalcoholassociatedliverdisease