Tim-4 in Health and Disease: Friend or Foe?

Tim-4 in Health and Disease: Friend or Foe?

T-cell immunoglobulin and mucin domain containing 4 (Tim-4) is a phosphatidylserine receptor and is selectively expressed on antigen presenting cells. Recently, Tim-4 was reported to be expressed on iNKT cells, B1 cells, and tumor cells, suggesting it has multiple biological functions. In this revie...

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Bibliographic Details
Main Authors: Wen Liu, Liyun Xu, Xiaohong Liang, Xiaojun Liu, Yangbing Zhao, Chunhong Ma, Lifen Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
Tim-4
macrophages
T cells
phosphatidylserine
immune regulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00537/full

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