Dynamics of Fibril Collagen Remodeling by Tumor Cells: A Model of Tumor-Associated Collagen Signatures

Dynamics of Fibril Collagen Remodeling by Tumor Cells: A Model of Tumor-Associated Collagen Signatures

Many solid tumors are characterized by a dense extracellular matrix (ECM) composed of various ECM fibril proteins. These proteins provide structural support and a biological context for the residing cells. The reciprocal interactions between growing and migrating tumor cells and the surrounding stro...

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Bibliographic Details
Main Authors: Sharan Poonja, Ana Forero Pinto, Mark C. Lloyd, Mehdi Damaghi, Katarzyna A. Rejniak
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
extracellular matrix (ECM)
ECM fibril patterns
Tumor-Associated Collagen Signature (TACS)
agent-based models
in silico modeling
MultiCell-LF model
Online Access:https://www.mdpi.com/2073-4409/12/23/2688

Internet

https://www.mdpi.com/2073-4409/12/23/2688

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