Relation between bone mineral density and coronary artery disease
Background: Osteoporosis and cardiovascular disease are the two important life threatening factors that cause morbidity and mortality. Previous studies had showed that bone mineral density is decreased with progression of atherosclerosis, and cardiovascular disease is more common in the osteoporotic...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Bushehr University of Medical Sciences
2015-01-01
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| Series: | Iranian South Medical Journal |
| Subjects: | |
| Online Access: | http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-550&slc_lang=en&sid=1 |
| _version_ | 1823999145437822976 |
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| author | Masoome Tohodi Mohammad Housein Dabbaghmanesh Javad Kojuri Masoome Khedri |
| author_facet | Masoome Tohodi Mohammad Housein Dabbaghmanesh Javad Kojuri Masoome Khedri |
| author_sort | Masoome Tohodi |
| collection | DOAJ |
| description | Background: Osteoporosis and cardiovascular disease are the two important life threatening factors that cause morbidity and mortality. Previous studies had showed that bone mineral density is decreased with progression of atherosclerosis, and cardiovascular disease is more common in the osteoporotic patients. The aim of this study is to evaluate the relationship between bone mineral density and coronary artery stenosis in patients who underwent coronary angiography .
Materials and Methods: In this study 197 patients (111female and 86 male) that underwent coronary angiography and bone mineral densitometry were evaluated. According to angiographic data ,patients were divided to two group :first group had coronary stenosis in ≥50% in one or more major coronary arteries and second group with normal coronary artery or stenosis <50%. Mean bone mineral density(gr/cm2)was measured in the lumbar spine and hip by using Dual Energy X-ray Absorptiometry (DEXA) and T-score was determined .T-score > -1 as normal , T-score -1 to -2.5 as osteopenia, and T-score <-2.5 as osteoporosis were described. Finally the relationship between coronary artery stenosis and bone mineral density was evaluated by SPSS statistical software version 15 with using suitable statistical test.
Results: The mean age of sample was 57±11.32). 33% of patients had osteoporosis in lumbar spine and 24.2% of them in femoral neck.Significant coronary artery stenosis were seen in 67.9% of patients. There were no significant difference between lumbar and hip bone mineral density in patients with significant coronary disease and subjects without coronary artery disease.
Conclusion: There were no associations between coronary artery disease and osteoporosis. Further studies are recommended for confirmation of this relationship. |
| first_indexed | 2024-12-18T17:39:30Z |
| format | Article |
| id | doaj.art-237db2baf09a4d9baf5ca0dcd6e74d54 |
| institution | Directory Open Access Journal |
| issn | 1735-4374 1735-6954 |
| language | English |
| last_indexed | 2024-12-18T17:39:30Z |
| publishDate | 2015-01-01 |
| publisher | Bushehr University of Medical Sciences |
| record_format | Article |
| series | Iranian South Medical Journal |
| spelling | doaj.art-237db2baf09a4d9baf5ca0dcd6e74d542022-12-21T20:59:14ZengBushehr University of Medical SciencesIranian South Medical Journal1735-43741735-69542015-01-0117611951202Relation between bone mineral density and coronary artery diseaseMasoome Tohodi0Mohammad Housein Dabbaghmanesh1Javad Kojuri2Masoome Khedri3 Endocrinology and Metabolism Research Center, Namazi Hospital , Shiraz university of medical science, Shiraz, IRAN Endocrinology and Metabolism Research Center, Namazi Hospital , Shiraz university of medical science, Shiraz, IRAN Depatment of Cardiology, Namazi Hospital, Shiraz University of Medical Science, Shiraz, IRAN Depatment of Internal Medicine, Shool of Medicine, AhvazUniversity of Medical Science, Ahvaz, IRAN Background: Osteoporosis and cardiovascular disease are the two important life threatening factors that cause morbidity and mortality. Previous studies had showed that bone mineral density is decreased with progression of atherosclerosis, and cardiovascular disease is more common in the osteoporotic patients. The aim of this study is to evaluate the relationship between bone mineral density and coronary artery stenosis in patients who underwent coronary angiography . Materials and Methods: In this study 197 patients (111female and 86 male) that underwent coronary angiography and bone mineral densitometry were evaluated. According to angiographic data ,patients were divided to two group :first group had coronary stenosis in ≥50% in one or more major coronary arteries and second group with normal coronary artery or stenosis <50%. Mean bone mineral density(gr/cm2)was measured in the lumbar spine and hip by using Dual Energy X-ray Absorptiometry (DEXA) and T-score was determined .T-score > -1 as normal , T-score -1 to -2.5 as osteopenia, and T-score <-2.5 as osteoporosis were described. Finally the relationship between coronary artery stenosis and bone mineral density was evaluated by SPSS statistical software version 15 with using suitable statistical test. Results: The mean age of sample was 57±11.32). 33% of patients had osteoporosis in lumbar spine and 24.2% of them in femoral neck.Significant coronary artery stenosis were seen in 67.9% of patients. There were no significant difference between lumbar and hip bone mineral density in patients with significant coronary disease and subjects without coronary artery disease. Conclusion: There were no associations between coronary artery disease and osteoporosis. Further studies are recommended for confirmation of this relationship.http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-550&slc_lang=en&sid=1Coronary artery disease Bone mineral density Osteoporosis Osteopenia |
| spellingShingle | Masoome Tohodi Mohammad Housein Dabbaghmanesh Javad Kojuri Masoome Khedri Relation between bone mineral density and coronary artery disease Iranian South Medical Journal Coronary artery disease Bone mineral density Osteoporosis Osteopenia |
| title | Relation between bone mineral density and coronary artery disease |
| title_full | Relation between bone mineral density and coronary artery disease |
| title_fullStr | Relation between bone mineral density and coronary artery disease |
| title_full_unstemmed | Relation between bone mineral density and coronary artery disease |
| title_short | Relation between bone mineral density and coronary artery disease |
| title_sort | relation between bone mineral density and coronary artery disease |
| topic | Coronary artery disease Bone mineral density Osteoporosis Osteopenia |
| url | http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-550&slc_lang=en&sid=1 |
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