Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activity
Essential oils of the leaves and flowers of Anthemis cotula L. (family Asteraceae) grown in Jordan were extracted by hydro-distillation and then analyzed by GC–MS. Sesquiterpenes hydrocarbons (SH) were the dominant components in the oils extracted from leaves and flowers of A. cotula. γ-Muurolene an...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-02-01
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| Series: | Arabian Journal of Chemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535222007869 |
| _version_ | 1797952755443171328 |
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| author | Lo'ay A. Al-Momani Sultan T. Abu-Orabi Haneen M. Hlail Rami Q. Alkhatib Yousef Al-Dalahmeh Mahmoud A. Al-Qudah |
| author_facet | Lo'ay A. Al-Momani Sultan T. Abu-Orabi Haneen M. Hlail Rami Q. Alkhatib Yousef Al-Dalahmeh Mahmoud A. Al-Qudah |
| author_sort | Lo'ay A. Al-Momani |
| collection | DOAJ |
| description | Essential oils of the leaves and flowers of Anthemis cotula L. (family Asteraceae) grown in Jordan were extracted by hydro-distillation and then analyzed by GC–MS. Sesquiterpenes hydrocarbons (SH) were the dominant components in the oils extracted from leaves and flowers of A. cotula. γ-Muurolene and aromadendrene, were the major compounds that were obtained from the flowers oil, while γ-muurolene and trans-cadinene ether were detected as major ingredients in the leaves extract. LC-MS analysis was carried out to identify the significant compounds from each extract. Additionally, butanol (B), aqueous methanol (M) and water (W) extracts prepared from the flowers and the leaves of A. cotula were analysed by LC-MS/MS. Apigenin and chlorogenic acid were the main constituents detected in the flowers’ alcoholic extracts and leaves’ aqueous extract. Moreover, the essential oils and all prepared extracts were assayed for their total antioxidant activity using the DPPH, ABTS, and ferrous ion chelating effect (FIC) assay methods. All investigated oils and extracts showed interesting activity as compared to the positive controls employed (α-tocopherol and ascorbic acid). |
| first_indexed | 2024-04-10T22:52:16Z |
| format | Article |
| id | doaj.art-2384c71a037f44a5b69053ec46d6c962 |
| institution | Directory Open Access Journal |
| issn | 1878-5352 |
| language | English |
| last_indexed | 2024-04-10T22:52:16Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arabian Journal of Chemistry |
| spelling | doaj.art-2384c71a037f44a5b69053ec46d6c9622023-01-15T04:21:37ZengElsevierArabian Journal of Chemistry1878-53522023-02-01162104470Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activityLo'ay A. Al-Momani0Sultan T. Abu-Orabi1Haneen M. Hlail2Rami Q. Alkhatib3Yousef Al-Dalahmeh4Mahmoud A. Al-Qudah5Department of Chemistry, The Hashemite University, P.O. Box 330127, Zarqa 13133, JordanDepartment of Chemistry, Faculty of Science, Yarmouk University, P.O. Box.566, Irbid 21163, Jordan; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tishk International University, Erbil 44001, Kurdistan Region, IraqDepartment of Chemistry, Faculty of Science, Yarmouk University, P.O. Box.566, Irbid 21163, JordanDepartment of Biotechnology and Genetic Engineering, Faculty of Science and Arts, Jordan University of Science and Technology, JordanDepartment of Basic Pharmaceutical Sciences, Faculty of pharmacy, Isra University, Amman, JordanDepartment of Chemistry, Faculty of Science, Yarmouk University, P.O. Box.566, Irbid 21163, Jordan; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia; Corresponding author.Essential oils of the leaves and flowers of Anthemis cotula L. (family Asteraceae) grown in Jordan were extracted by hydro-distillation and then analyzed by GC–MS. Sesquiterpenes hydrocarbons (SH) were the dominant components in the oils extracted from leaves and flowers of A. cotula. γ-Muurolene and aromadendrene, were the major compounds that were obtained from the flowers oil, while γ-muurolene and trans-cadinene ether were detected as major ingredients in the leaves extract. LC-MS analysis was carried out to identify the significant compounds from each extract. Additionally, butanol (B), aqueous methanol (M) and water (W) extracts prepared from the flowers and the leaves of A. cotula were analysed by LC-MS/MS. Apigenin and chlorogenic acid were the main constituents detected in the flowers’ alcoholic extracts and leaves’ aqueous extract. Moreover, the essential oils and all prepared extracts were assayed for their total antioxidant activity using the DPPH, ABTS, and ferrous ion chelating effect (FIC) assay methods. All investigated oils and extracts showed interesting activity as compared to the positive controls employed (α-tocopherol and ascorbic acid).http://www.sciencedirect.com/science/article/pii/S1878535222007869Anthemis cotula L.Chemical compositionAntioxidant activityEssential oilLC-MS/MS |
| spellingShingle | Lo'ay A. Al-Momani Sultan T. Abu-Orabi Haneen M. Hlail Rami Q. Alkhatib Yousef Al-Dalahmeh Mahmoud A. Al-Qudah Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activity Arabian Journal of Chemistry Anthemis cotula L. Chemical composition Antioxidant activity Essential oil LC-MS/MS |
| title | Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activity |
| title_full | Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activity |
| title_fullStr | Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activity |
| title_full_unstemmed | Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activity |
| title_short | Anthemis cotula L. from Jordan: Essential oil composition, LC-ESI-MS/MS profiling of phenolic acids - flavonoids and in vitro antioxidant activity |
| title_sort | anthemis cotula l from jordan essential oil composition lc esi ms ms profiling of phenolic acids flavonoids and in vitro antioxidant activity |
| topic | Anthemis cotula L. Chemical composition Antioxidant activity Essential oil LC-MS/MS |
| url | http://www.sciencedirect.com/science/article/pii/S1878535222007869 |
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