Reconstruction of the Swine Pulmonary Artery Using a Graft Engineered With Syngeneic Cardiac Pericytes

Reconstruction of the Swine Pulmonary Artery Using a Graft Engineered With Syngeneic Cardiac Pericytes

The neonatal heart represents an attractive source of regenerative cells. Here, we report the results of a randomized, controlled, investigator-blinded preclinical study, which assessed the safety and effectiveness of a matrix graft cellularized with cardiac pericytes (CPs) in a piglet model of pulm...

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Bibliographic Details
Main Authors: Valeria Vincenza Alvino, Anita C. Thomas, Mohamed T. Ghorbel, Filippo Rapetto, Srinivas A. Narayan, Michael Kilcooley, Dominga Iacobazzi, Michele Carrabba, Marco Fagnano, William Cathery, Elisa Avolio, Massimo Caputo, Paolo Madeddu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
pericytes
grafts
congenital heart disease
pulmonary artery
tissue engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.715717/full

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