Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation

A novel type of spiral micromixer with expansion and contraction parts is presented in order to enhance the mixing quality in the low Reynolds number regimes for point-of-care tests (POCT). Three classes of micromixers with different numbers of loops and modified geometries were studied. Numerical s...

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Main Authors: Pouya Mehrdel, Shadi Karimi, Josep Farré-Lladós, Jasmina Casals-Terré
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/9/11/552
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author Pouya Mehrdel
Shadi Karimi
Josep Farré-Lladós
Jasmina Casals-Terré
author_facet Pouya Mehrdel
Shadi Karimi
Josep Farré-Lladós
Jasmina Casals-Terré
author_sort Pouya Mehrdel
collection DOAJ
description A novel type of spiral micromixer with expansion and contraction parts is presented in order to enhance the mixing quality in the low Reynolds number regimes for point-of-care tests (POCT). Three classes of micromixers with different numbers of loops and modified geometries were studied. Numerical simulation was performed to study the flow behavior and mixing performance solving the steady-state Navier&#8315;Stokes and the convection-diffusion equations in the Reynolds range of 0.1&#8315;10.0. Comparisons between the mixers with and without expansion parts were made to illustrate the effect of disturbing the streamlines on the mixing performance. Image analysis of the mixing results from fabricated micromixers was used to verify the results of the simulations. Since the proposed mixer provides up to 92% of homogeneity at <i>Re</i> 1.0, generating 442 Pa of pressure drop, this mixer makes a suitable candidate for research in the POCT field.
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spelling doaj.art-238fa277ac694094af96d37d4f5b7f132022-12-22T00:04:34ZengMDPI AGMicromachines2072-666X2018-10-0191155210.3390/mi9110552mi9110552Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental ValidationPouya Mehrdel0Shadi Karimi1Josep Farré-Lladós2Jasmina Casals-Terré3Mechanical Engineering Department—MicroTech Lab., Universitat Politècnica de Catalunya, Colom 7-11 08222 Terrassa, Barcelona, SpainMechanical Engineering Department—MicroTech Lab., Universitat Politècnica de Catalunya, Colom 7-11 08222 Terrassa, Barcelona, SpainMechanical Engineering Department—MicroTech Lab., Universitat Politècnica de Catalunya, Colom 7-11 08222 Terrassa, Barcelona, SpainMechanical Engineering Department—MicroTech Lab., Universitat Politècnica de Catalunya, Colom 7-11 08222 Terrassa, Barcelona, SpainA novel type of spiral micromixer with expansion and contraction parts is presented in order to enhance the mixing quality in the low Reynolds number regimes for point-of-care tests (POCT). Three classes of micromixers with different numbers of loops and modified geometries were studied. Numerical simulation was performed to study the flow behavior and mixing performance solving the steady-state Navier&#8315;Stokes and the convection-diffusion equations in the Reynolds range of 0.1&#8315;10.0. Comparisons between the mixers with and without expansion parts were made to illustrate the effect of disturbing the streamlines on the mixing performance. Image analysis of the mixing results from fabricated micromixers was used to verify the results of the simulations. Since the proposed mixer provides up to 92% of homogeneity at <i>Re</i> 1.0, generating 442 Pa of pressure drop, this mixer makes a suitable candidate for research in the POCT field.https://www.mdpi.com/2072-666X/9/11/552point-of-carepassive mixermicromixerspiral micromixermixing
spellingShingle Pouya Mehrdel
Shadi Karimi
Josep Farré-Lladós
Jasmina Casals-Terré
Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation
Micromachines
point-of-care
passive mixer
micromixer
spiral micromixer
mixing
title Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation
title_full Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation
title_fullStr Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation
title_full_unstemmed Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation
title_short Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation
title_sort novel variable radius spiral shaped micromixer from numerical analysis to experimental validation
topic point-of-care
passive mixer
micromixer
spiral micromixer
mixing
url https://www.mdpi.com/2072-666X/9/11/552
work_keys_str_mv AT pouyamehrdel novelvariableradiusspiralshapedmicromixerfromnumericalanalysistoexperimentalvalidation
AT shadikarimi novelvariableradiusspiralshapedmicromixerfromnumericalanalysistoexperimentalvalidation
AT josepfarrellados novelvariableradiusspiralshapedmicromixerfromnumericalanalysistoexperimentalvalidation
AT jasminacasalsterre novelvariableradiusspiralshapedmicromixerfromnumericalanalysistoexperimentalvalidation